DCDC2

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DCDC2

Official Full Name doublecortin domain containing 2
Background This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. Mutations in this gene have been associated with Reading Disability (RD), also referred to as developmental dyslexia. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Synonyms DCDC2; doublecortin domain containing 2; doublecortin domain-containing protein 2; DCDC2A; KIAA1154; RU2; DCDC 2; DCDC2_HUMAN; HGNC:18141; Protein RU2S; RU2S; RU2S protein; OTTHUMP00000017887
    • Species :
    • Human
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DCDC2-301165H Recombinant Human DCDC2 protein, GST-tagged E.coli GST
    Human DCDC2-2389H Recombinant Human DCDC2 Protein, GST-tagged Wheat Germ GST
    Human DCDC2-3063H Recombinant Human DCDC2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human DCDC2-7052HCL Recombinant Human DCDC2 293 Cell Lysate HEK293 N/A
    Rat DCDC2-1792R Recombinant Rat DCDC2 Protein Mammalian Cell His

    DCDC2 involved in several pathways and played different roles in them. We selected most pathways DCDC2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DCDC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    DCDC2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DCDC2 itself. We selected most functions DCDC2 had, and list some proteins which have the same functions with DCDC2. You can find most of the proteins on our site.

    Function Related Protein
    protein binding NR1H2; TRAPPC6A; CDC37; NRIP1; GP9; NEDD9; ALOX5AP; RAD52; PSMB7; ZNF511

    DCDC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DCDC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DCDC2.

    NIF3L1; MRFAP1

    Truong, DT; Che, A; et al. Mutation of Dcdc2 in mice leads to impairments in auditory processing and memory ability. GENES BRAIN AND BEHAVIOR 13:802-811(2014).
    Inokawa, Y; Nomoto, S; et al. Detection of doublecortin domain-containing 2 (DCDC2), a new candidate tumor suppressor gene of hepatocellular carcinoma, by triple combination array analysis. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH 32:-(2013).

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