| Description : |
This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
133.9 kDa |
| AA Sequence : |
MLLTLIILLPVVSKFSFVSLSAPQH WSCPEGTLAGNGNSTCVGPAPFLIF SHGNSIFRIDTEGTNYEQLVVDAGV SVIMDFHYNEKRIYWVDLERQLLQR VFLNGSRQERVCNIEKNVSGMAINW INEEVIWSNQQEGIITVTDMKGNNS HILLSALKYPANVAVDPVERFIFWS SEVAGSLYRADLDGVGVKALLETSE KITAVSLDVLDKRLFWIQYNREGSN SLICSCDYDGGSVHISKHPTQHNLF AMSLFGDRIFYSTWKMKTIWIANKH TGKDMVRINLHSSFVPLGELKVVHP LAQPKAEDDTWEPEQKLCKLRKGNC SSTVCGQDLQSHLCMCAEGYALSRD RKYCEDVNECAFWNHGCTLGCKNTP GSYYCTCPVGFVLLPDGKRCHQLVS CPRNVSECSHDCVLTSEGPLCFCPE GSVLERDGKTCSGCSSPDNGGCSQL CVPLSPVSWECDCFPGYDLQLDEKS CAASGPQPFLLFANSQDIRHMHFDG TDYGTLLSQQMGMVYALDHDPVENK IYFAHTALKWIERANMDGSQRERLI EEGVDVPEGLAVDWIGRRFYWTDRG KSLIGRSDLNGKRSKIITKENISQP RGIAVHPMAKRLFWTDTGINPRIES SSLQGLGRLVIASSDLIWPSGITID FLTDKLYWCDAKQSVIEMANLDGSK RRRLTQNDVGHPFAVAVFEDYVWFS DWAMPSVIRVNKRTGKDRVRLQGSM LKPSSLVVVHPLAKPGADPCLYQNG GCEHICKKRLGTAWCSCREGFMKAS DGKTCLALDGHQLLAGGEVDLKNQV TPLDILSKTRVSEDNITESQHMLVA EIMVSDQDDCAPVGCSMYARCISEG EDATCQCLKGFAGDGKLCSDIDECE MGVPVCPPASSKCINTEGGYVCRCS EGYQGDGIHCLDIDECQLGVHSCGE NASCTNTEGGYTCMCAGRLSEPGLI CPDSTPPPHLREDDHHYSVRNSDSE CPLSHDGYCLHDGVCMYIEALDKYA CNCVVGYIGERCQYRDLKWWELRHA GHGQQQKVIVVAVCVVVLVMLLLLS LWGAHYYRTQKLLSKNPKNPYEESS RDVRSRRPADTEDGMSSCPQPWFVV IKEHQDLKNGGQPVAGEDGQAADGS MQPTSWRQEPQLCGMGTEQGCWIPV SSDKGSCPQVMERSFHMPSYGTQTL EGGVEKPHSLLSANPLWQQRALDPP HQMELTQTRTRPLEQKLISEEDLAA NDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
