| Description : |
The protein encoded by this gene is essential for bone resorption, and may play a critical role in vesicular transport in the osteoclast. Mutations in this gene are associated with autosomal recessive osteopetrosis type 6 (OPTB6). Alternatively spliced transcript variants have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
117.4 kDa |
| AA Sequence : |
MLSVVENGLDPQAAIPVIKKKLVGS VKALQKQYVSLDTVVTSEDGDANTM CSALEAVFIHGLHAKHIRAEAGGKR KKSAHQKPLPQPVFWPLLKAVTHKH IISELEHLTFVNTDVGRCRAWLRLA LNDGLMECYLKLLLQEQARLHEYYQ PTALLRDAEEGEFLLSFLQGLTSLS FELSYKSAILNEWTLTPLALSGLCP LSELDPLSTSGAELQRKESLDSISH SSGSEDIEVHHSGHKIRRNQKLTAS SLSLDTASSSQLSCSLNSDSCLLQE NGSKSPDHCEEPMSCDSDLGTANAE DSDRSLQEVLLEFSKAQVNSVPTNG LSQETEIPTPQASLSLHGLNTSTYL HCEAPAEPLPAQAASGTQDGVHVQE PRPQAPSPLDLQQPVESTSGQQPSS TVSETAREVGQGNGLQKAQAHDGAG LKLVVSSPTSPKNKSWISEDDFYRP SREQPLESASDHPIASYRGTPGSRP GLHRHFSQEPRKNCSLGALDQACVP SPGRRQAQAAPSQGHKSFRVVHRRQ MGLSNPFRGLMKLGTVERRGAMGIW KELFCELSPLEFRLYLSNEEHTCVE NCSLLRCESVGPAHSDGRFELVFSG KKLALRASSQDEAEDWLDRVREALQ KVRPQQEDEWVNVQYPDQPEEPPEA PQGCLSPSDLLSEPAALQGTQFDWS SAQVPEPDAIKESLLYLYMDRTWMP YIFSLSLEALKCFRIRNNEKMLSDS HGVETIRDILPDTSLGGPSFFKIIT AKAVLKLQAGNAEEAALWRDLVRKV LASYLETAEEAVTLGGSLDENCQEV LKFATRENGFLLQYLVAIPMEKGLD SQGCFCAGCSRQIGFSFVRPKLCAF SGLYYCDICHQDDASVIPARIIHNW DLTKRPICRQALKFLTQIRAQPLIN LQMVNASLYEHVERMHLIGRRREQL KLLGDYLGLCRSGALKELSKRLNHR NYLLESPHRFSVADLQQIADGVYEG FLKALIEFASQHVYHCDLCTQRGFI CQICQHHDIIFPFEFDTTVRCAECK TVFHQSCQAVVKKGCPRCARRRKYQ EQNIFASGPTRTRPLEQKLISEEDL AANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
