|Official Full Name||pleckstrin homology domain containing, family M (with RUN domain) member 1|
|Background||The protein encoded by this gene is essential for bone resorption, and may play a critical role in vesicular transport in the osteoclast. Mutations in this gene are associated with autosomal recessive osteopetrosis type 6 (OPTB6). Alternatively spliced transcript variants have been found for this gene.|
|Synonyms||PLEKHM1; pleckstrin homology domain containing, family M (with RUN domain) member 1; pleckstrin homology domain-containing family M member 1; KIAA0356; 162 kDa adapter protein; AP162; PH domain-containing family M member 1; PKHM1_HUMAN; B2; OPTB6|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
PLEKHM1 involved in several pathways and played different roles in them. We selected most pathways PLEKHM1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PLEKHM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
PLEKHM1 has several biochemical functions, for example, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLEKHM1 itself. We selected most functions PLEKHM1 had, and list some proteins which have the same functions with PLEKHM1. You can find most of the proteins on our site.
|metal ion binding||YME1L1; CACNA2D1; LIG4; KLF5; NSF; PARP12B; ZEB2A; XPA; ZNF221; NEK10|
|protein binding||DHX16; DNAJA1; TDO2; ARID1A; AMIGO2; NUBP2; FYN; DOK6; ITGA2B; CEACAM6|
PLEKHM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLEKHM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLEKHM1.