Recombinant Human PRKAA1 Protein (K45R)
Cat.No. : | PRKAA1-01H |
Product Overview : | Recombinant AMPKalpha Protein (K45R) without tag was expressed in E.coli. |
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- Gene Information
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Description : | The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
Source : | E. coli |
Species : | Human |
Molecular Mass : | The protein has a calculated MW of 65 kDa. |
AA Sequence : | MHHHHHHMRRLSSWRKMATAEKQKH DGRVKIGHYILGDTLGVGTFGKVKV GRHELTGHKVAVKILNRQKIRSLDV VGKIRREIQNLKLFRHPHIIKLYQV ISTPSDIFMVMEYVSGGELFDYICK NGRLDEKESRRLFQQILSGVDYCHR HMVVHRDLKPENVLLDAHMNAKIAD FGLSNMMSDGEFLRTSCGSPNYAAP EVISGRLYAGPEVDIWSSGVILYAL LCGTLPFDDDHVPTLFKKICDGIFY TPQYLNPSVISLLKHMLQVDPMKRA TIKDIREHEWFKQDLPKYLFPEDPS YSSTMIDDEALKEVCEKFECSEEEV LSCLYNRNHQDPLAVAYHLIIDNRR IMNEAKDFYLATSPPDSFLDDHHLT RPHPERVPFLVAETPRARHTLDELN PQKSKHQGVRKAKWHLGIRSQSRPN DIMAEVCRAIKQLDYEWKVVNPYYL RVRRKNPVTSTYSKMSLQLYQVDSR TYLLDFRSIDDEITEAKSGTATPQR SGSVSNYRSCQRSDSDAEAQGKSSE VSLTSSVTSLDSSPVDLTPRPGSHT IEFFEMCANLIKILAQ |
Purity : | >85% by SDS-PAGE |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Concentration : | 0.136 mg/mL |
Storage Buffer : | PBS pH7.4, 0.1% SKL |
Gene Name : | PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 [ Homo sapiens (human) ] |
Official Symbol : | PRKAA1 |
Synonyms : | PRKAA1; protein kinase AMP-activated catalytic subunit alpha 1; AMPK; AMPKa1; AMPK alpha 1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase, catalytic alpha-1 chain; ACACA kinase; AMP -activate kinase alpha 1 subunit; AMP-activated protein kinase, catalytic, alpha-1; AMPK subunit alpha-1; AMPK, alpha, 1; HMGCR kinase; acetyl-CoA carboxylase kinase; hydroxymethylglutaryl-CoA reductase kinase; protein kinase, AMP-activated, alpha 1 catalytic subunit; tau-protein kinase PRKAA1; EC 2.7.11.1; EC 2.7.11.26; EC 2.7.11.27; EC 2.7.11.31 |
Gene ID : | 5562 |
mRNA Refseq : | NM_006251 |
Protein Refseq : | NP_006242 |
MIM : | 602739 |
UniProt ID : | Q13131 |
Products Types
◆ Recombinant Protein | ||
PRKAA1-1762H | Recombinant Human PRKAA1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PRKAA1-4327R | Recombinant Rat PRKAA1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PRKAA1-06H | Recombinant Human PRKAA1 complex Protein, N-Flag-tagged | +Inquiry |
PRKAA1-147H | Recombinant Human PRKAA1 Protein, His-tagged | +Inquiry |
PRKAA1-007H | Active Recombinant Human PRKAA1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PRKAA1-1412HCL | Recombinant Human PRKAA1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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