| Description : |
The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
43.1 kDa |
| Protein Length : |
943 |
| AA Sequence : |
MARGSALPRRPLLCIPAVWAAAALL LSVSRTSGEVEVLDPNDPLGPLDGQ DGPIPTLKGYFLNFLEPVNNITIVQ GQTAILHCKVAGNPPPNVRWLKNDA PVVQEPRRIIIRKTEYGSRLRIQDL DTTDTGYYQCVATNGMKTITATGVL FVRLGPTHSPNHNFQDDYHEDGFCQ PYRGIACARFIGNRTIYVDSLQMQG EIENRITAAFTMIGTSTHLSDQCSQ FAIPSFCHFVFPLCDARSRTPKPRE LCRDECEVLESDLCRQEYTIARSNP LILMRLQLPKCEALPMPESPDAANC MRIGIPAERLGRYHQCYNGSGMDYR GTASTTKSGHQCQPWALQHPHSHHL SSTDFPELGGGHAYCRNPGGQMEGP WCFTQNKNVRMELCDVPSCSPRDSS KMGILYILVPSIAIPLVIACLFFLV CMCRNKQKASASTPQRRQLMASPSQ DMEMPLINQHKQAKLKEISLSAVRF MEELGEDRFGKVYKGHLFGPAPGEQ TQAVAIKTLKDKAEGPLREEFRHEA MLRARLQHPNVVCLLGVVTKDQPLS MIFSYCSHGDLHEFLVMRSPHSDVG STDDDRTVKSALEPPDFVHLVAQIA AGMEYLSSHHVVHKDLATRNVLVYD KLNVKISDLGLFREVYAADYYKLLG NSLLPIRWMAPEAIMYGKFSIDSDI WSYGVVLWEVFSYGLQPYCGYSNQD VVEMIRNRQVLPCPDDCPAWVYALM IECWNEFPSRRPRFKDIHSRLRAWG NLSNYNSSAQTSGASNTTQTSSLST SPVSNVSNARYVGPKQKAPPFPQPQ FIPMKGQIRPMVPPPQLYVPVNGYQ PVPAYGAYLPNFYPVQIPMQMAPQQ VPPQMVPKPSSHHSGSGSTSTGYVT TAPSNTSMADRAALLSEGADDTQNA PEDGAQSTVQEAEEEEEGSVPETEL LGDCDTLQVDEAQVQLEA |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
