ROR2

  • Official Full Name

    receptor tyrosine kinase-like orphan receptor 2

  • Overview

    ROR1 and ROR2 are orphan receptor tyrosine kinases that are most closely related to MuSK and the Trk family of neurotrophin receptors. They are characterized by the presence of extracellular frizzled-like cysteine-rich domains and membrane-proximal kringl
  • Synonyms

    ROR2; receptor tyrosine kinase-like orphan receptor 2; BDB, BDB1, NTRKR2; tyrosine-protein kinase transmembrane receptor ROR2; neurotrophic tyrosine kinase receptor-related 2; BDB; BDB1; NTRKR2; MGC163394;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • C
  • His
  • DDK
  • DDK|His
  • Fc
  • Flag
  • GST
  • hFc
  • His (Fc)
  • Avi
  • His|GST
  • human|IgG1|Fc
  • Myc
  • Myc|DDK
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ROR2-30436TH Active Recombinant Human ROR2, GST-tagged Sf9 Insect Cell GST
Human ROR2-757H Recombinant Human ROR2 Protein, DDK/His-tagged HEK293 DDK/His
Human ROR2-668H Recombinant Human ROR2, Fc-tagged, Biotinylated Human Cell Fc
Human ROR2-183H Recombinant Human ROR2 protein, Fc-tagged HEK293 human/IgG1/Fc Glu34-Gly403
Human ROR2-758H Recombinant Human ROR2 Protein, DDK-tagged Sf9 Insect Cell DDK
Human ROR2-1184H Recombinant Human ROR2 protein, His & GST-tagged E.coli His/GST Trp683~Val934
Human ROR2-423H Recombinant Human ROR2, GST-tagged, Active Sf9 Insect Cell GST
Human ROR2-667H Recombinant Human ROR2, His-tagged, Biotinylated Human Cell His
Human ROR2-669H Recombinant Human ROR2, His-tagged Human Cell His
Human ROR2-799H Recombinant Human ROR2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human ROR2-5808H Recombinant Human ROR2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ROR2-666H Recombinant Human ROR2 protein, His&Avi-tagged, Biotinylated HEK293 His&Avi Met1-Gly403
Human ROR2-183HP Recombinant Human ROR2 protein, Fc-tagged, R-PE labeled HEK293 Fc
Human ROR2-313H Active Recombinant Human ROR2 protein, His-tagged HEK293 His Glu 34 - Gly 403
Human ROR2-433H Recombinant Human ROR2 Protein, His-tagged HEK293 His 943
Human ROR2-145H Recombinant Human ROR2 protein, His-Avi-tagged HEK293 His-Avi Val 34-Gly 403
Human ROR2-183HAF555 Recombinant Human ROR2 Protein, hFc-tagged, Alexa Fluor 555 conjugated HEK293 hFc Glu34-Gly403
Human ROR2-183HAF488 Recombinant Human ROR2 Protein, hFc-tagged, Alexa Fluor 488 conjugated HEK293 hFc Glu34-Gly403
Human ROR2-434H Recombinant Human ROR2 Protein, Fc-tagged HEK293 Fc 943
Human ROR2-1130HFL Recombinant Full Length Human ROR2 Protein, C-Flag-tagged Mammalian cells Flag
Human ROR2-5879H Recombinant Human ROR2 Protein (Glu34-Tyr406), C-His tagged Mammalian cells C-His Glu34-Tyr406
Human ROR2-183HAF647 Recombinant Human ROR2 Protein, hFc-tagged, Alexa Fluor 647 conjugated HEK293 hFc Glu34-Gly403
Human ROR2-435H Recombinant Human ROR2 Protein, Fc-tagged HEK293 Fc 943
Human ROR2-183HF Recombinant Human ROR2 Protein, hFc-tagged, FITC conjugated HEK293 hFc Glu34-Gly403
Human ROR2-1906H-B Recombinant Human ROR2 Protein Pre-coupled Magnetic Beads HEK293
Human ROR2-1906H Recombinant Human ROR2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ROR2-0259H Recombinant Human ROR2 protein, His-tagged HEK293 His Met1-Gly403
Human ROR2-0651H Active Recombinant Human ROR2 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Glu34-Gly403
Human ROR2-183HA Recombinant Human ROR2 protein, Fc-tagged, APC labeled HEK293 Fc
Human ROR2-0653H Active Recombinant Human ROR2 protein, Fc-tagged HEK293 Fc Glu34-Gly403
Human ROR2-5880H Recombinant Human ROR2 Protein (Trp683-Thr923), N-GST tagged E.coli N-GST Trp683-Thr923
Mouse ROR2-0652M Recombinant Mouse ROR2 protein, Fc-tagged HEK293 Fc Glu34-Gly403
Mouse Ror2-5573M Recombinant Mouse Ror2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse ROR2-314M Recombinant Mouse ROR2 protein, Fc-tagged HEK293 human/IgG1/Fc 370
Chicken ROR2-3611C Recombinant Chicken ROR2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

ROR2 involved in several pathways and played different roles in them. We selected most pathways ROR2 participated on our site, such as Beta-catenin independent WNT signaling, Cardiac Progenitor Differentiation, Noncanonical Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ROR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Beta-catenin independent WNT signalingITPR2;ROR2;DVL3;AP2A1;ROR1;DVL2;AP2S1;AGO2;CLTB
Cardiac Progenitor DifferentiationTBX5;TBX20;LIN28B;NKX2;SOX1;LIN28A;ROR2;BMP1;T
Noncanonical Wnt signaling pathwayCHD7;ROR2;CTHRC1
PCP/CE pathwayPRICKLE1;PRICKLE1B;ROR1;ROR2;RYK
Signal TransductionRGS7;TAGAPB;RBP4;OMG;STARD8;IFT52;MYO7A;IQGAP3;PRICKLE1B
Signaling by WntAES;SRY;BCL9L;SOX6;RSPO3;KLHL12;ROR1;RNF43;SOX32
WNT5A-dependent internalization of FZD2, FZD5 and ROR2ROR1;ROR2
Wnt Signaling Pathway NetPathMTAP1B;TCF4;SOX1;TAX1BP3;CSNK2A1P;SALL1;ROR2;BRD7;NR5A1

ROR2 has several biochemical functions, for example, ATP binding, Wnt-protein binding, frizzled binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ROR2 itself. We selected most functions ROR2 had, and list some proteins which have the same functions with ROR2. You can find most of the proteins on our site.

Function Related Protein
ATP bindingSUCLG2;PANK3;NTRK2B;SYK;MB21D1;HSPA12B;MAP2K2B;TGFBR2;SGK1
Wnt-protein bindingLRP6;FZD7;LRP2A;FZD8;EVLA;LRP5;FZD1;FZD9;FZD8B
frizzled bindingWNT8A;BAMBI;WNT3;NDP;MYOC;LRP6;FZD1;WNT7A;SFRP1
metal ion bindingCPEB1B;PRICKLE1A;TRIM26;NT5C2A;KARS;HELZ;SOD3A;BCL11AA;ZFYVE16
protein bindingMATN3;HTN1;HIST2H3C;MAP2K2;NCSTN;CSTF2;FAT4;TFB1M;MED8
transmembrane receptor protein tyrosine kinase activityLTK;EK1;NTRK3;TEK;DDR2;ERBB3A;NPTN;ERBB4;EPHB4

ROR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ROR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ROR2.

HSP90AB1

Research Area

Related articles

Ishizuya-Oka, A; Kajita, M; et al. Thyroid Hormone-Regulated Wnt5a/Ror2 Signaling Is Essential for Dedifferentiation of Larval Epithelial Cells into Adult Stem Cells in the Xenopus laevis Intestine. PLOS ONE 9:-(2014).
Bauer, M; Benard, J; et al. WNT5A Encodes Two Isoforms with Distinct Functions in Cancers. PLOS ONE 8:-(2013).
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