ROR1

  • Official Full Name

    receptor tyrosine kinase-like orphan receptor 1

  • Overview

    ROR1 and ROR2 are orphan receptor tyrosine kinases that are most closely related to MuSK and the Trk family of neurotrophin receptors. They are characterized by the presence of extracellular frizzled-like cysteine-rich domains and membrane-proximal kringl
  • Synonyms

    ROR1; receptor tyrosine kinase-like orphan receptor 1; NTRKR1; tyrosine-protein kinase transmembrane receptor ROR1; neurotrophic tyrosine kinase receptor-related 1; neurotrophic tyrosine kinase, receptor-related 1; dJ537F10.1; MGC99659;

  • Recombinant Proteins
  • GMP Proteins
  • Cell & Tissue Lysates
  • Chromatography Reagents
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Human / Cynomolgus / Rhesus macaque
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293 cells
  • HEK293T
  • Human Cell
  • Human cells
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Mammalian cells
  • NS0
  • Sf9 Insect Cell
  • Wheat Germ
  • Yeast
  • Avi
  • C
  • 6His
  • His
  • mFc
  • DDK|His
  • DYKDDDDK
  • Fc
  • Flag
  • GST
  • hFc
  • His (Fc)
  • Strep
  • His\Avi
  • human|IgG1|Fc
  • Myc
  • DDK
  • N/A
  • N
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ROR1-198H Active Recombinant Human ROR1 protein, His-tagged HEK293 His Gln 30 - Glu 403
Human ROR1-232H Active Recombinant Human ROR1, GST-tagged Sf9 Insect Cell GST
Human ROR1-1811H Active Recombinant Human ROR1 protein, Fc-Avi-tagged, Biotinylated HEK293 Fc-Avi Gln 30 - Glu 403
Human ROR1-312H Active Recombinant Human ROR1 protein, Avi-tagged, Biotinylated HEK293 Avi Gln 30 - Glu 403
Human ROR1-1810H Active Recombinant Human ROR1 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Gln 30 - Glu 403
Human ROR1-014HG Active GMP Recombinant Human ROR1 protein HEK293 DNA sequence encoding Human ROR1(UniProtKB/Swiss-Prot: Q01973) was expressed with His tag at the C-terminal.
Human ROR1-051H Active Recombinant Human ROR1 protein, Fc/Avi-tagged, Biotinylated HEK293 cells Fc/Avi Ala24-Glu403
Human ROR1-2130H Active Recombinant Human ROR1 protein, mFc-tagged HEK293 mFc Gln 30 - Glu 403
Human ROR1-093HG Active GMP Recombinant Human ROR1 protein, Fc-tagged HEK293 Fc DNA sequence encoding Human B7-H4(UniProtKB/Swiss-Prot: Q01973) was expressed with Fc tag at the C-terminal.
Human ROR1-1812H Recombinant Human ROR1 protein, His-tagged HEK293 His AA Glu 39 - Gly 151
Human ROR1-756H Recombinant Human ROR1 Protein, DDK/His-tagged HEK293 DDK/His
Human ROR1-387H Recombinant Human ROR1 protein, Fc-tagged HEK293 Fc Met1-Glu403
Human ROR1-755H Recombinant Human ROR1 Protein, DDK/His-tagged HEK293 DDK/His
Human ROR1-1813H Recombinant Human ROR1 protein, His-tagged HEK293 His AA Glu 165 - Asp 305
Human ROR1-30958TH Recombinant Human ROR1 Wheat Germ N/A 100 amino acids
Human ROR1-666H Recombinant Human ROR1, Fc-tagged, Biotinylated Human Cell Fc
Human ROR1-540H Recombinant Human ROR1, His-GST tagged Insect Cell Fc
Human ROR1-1814H Recombinant Human ROR1 protein, His-tagged HEK293 His AA Asn 308 - Asp 395
Human ROR1-2358H Recombinant Human ROR1, His-tagged E.coli His 250-364aa
Human ROR1-88H Recombinant Human ROR1 protein, T7/His-tagged E.coli T7/His
Human ROR1-1815H Recombinant Human ROR1 protein, Fc-tagged HEK293 Fc AA Gln 30 - Glu 403
Human ROR1-7814H Recombinant Human ROR1 protein, Avi-tagged HEK293 Avi Gln 30 - Glu 403
Human ROR1-002HCL Recombinant Human ROR1 cell lysate Insect Cell N/A
Human ROR1-001HCL Recombinant Human ROR1 cell lysate Human Cell N/A
Human ROR1-198HAF488 Recombinant Human ROR1 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His
Human ROR1-512H Recombinant Human ROR1 Protein, His-tagged E.coli His Gly540~Gly795
Human ROR1-1815HP Recombinant Human ROR1 protein, Fc-tagged, R-PE labeled HEK293 Fc
Human ROR1-2213H Active Recombinant Human ROR1 protein, His&GST-tagged Insect Cells His/GST Met453-Asn783
Human ROR1-387HAF488 Recombinant Human ROR1 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc Met1-Glu403, 615
Human ROR1-198HA Recombinant Human ROR1 protein, His-tagged, APC labeled HEK293 His
Human ROR1-198HP Recombinant Human ROR1 protein, His-tagged, R-PE labeled HEK293 His
Human ROR1-4685H Active Recombinant Human ROR1 Protein, His-tagged, PE-Labeled HEK293 His Gln 30 - Glu 403
Human ROR1-10H Recombinant Human ROR1 Protein, C-6His-Avi tagged, Biotinylated Human Cell C-6His-Avi Gln30-Glu403
Human ROR1-595H Recombinant Human ROR1 Protein (Met1-Glu403), Biotinylated HEK293 N/A Met1-Glu403
Human ROR1-014M ROR1-coupled magnetic beads
Human ROR1-9875M Whole Blood ROR1 Antibody-coupled magnetic MicroBeads
Human ROR1-182H Recombinant Human ROR1 Protein, His\Avi-tagged Human Cell His\Avi
Human ROR1-973H Recombinant Human ROR1 protein, His-Avi-tagged HEK293 His-Avi Met1-Glu403
Human ROR1-1760H Recombinant Human ROR1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ROR1-1064H Recombinant Human ROR1 protein(Met1-Glu403), His-tagged HEK293 C-His Met1-Glu403
Human ROR1-425H Recombinant Human ROR1 Protein, His-tagged HEK293 His 937
Human ROR1-1820H Recombinant Human ROR1 protein, mFc-tagged HEK293 mFc Gln 30 - Glu 403
Human ROR1-1934H Recombinant Human ROR1 protein, His-tagged HEK293 His Gln 30 - Glu 403
Human ROR1-429H Recombinant Human ROR1 Protein, Fc-tagged HEK293 Fc 937
Human ROR1-426H Recombinant Human ROR1 Protein, His and Strep-tagged HEK293 His and Strep 937
Human ROR1-1935H Active Recombinant Human ROR1 protein, His-tagged, FITC-Labeled HEK293 His Gln 30 - Glu 403
Human ROR1-3437H Recombinant Human ROR1 protein, His-tagged E.coli His 30-391aa
Human ROR1-962H Recombinant Human ROR1 Protein, His-tagged Human cells His
Human ROR1-427H Recombinant Human ROR1 Protein, His-tagged HEK293 His 937
Human ROR1-1936H Active Recombinant Human ROR1 protein, Fc-tagged, FITC-Labeled HEK293 Fc Gln 30 - Glu 403
Human ROR1-387HAF555 Recombinant Human ROR1 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc Met1-Glu403, 615
Human ROR1-198HAF555 Recombinant Human ROR1 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His
Human ROR1-961H Recombinant Human ROR1 Protein, DYKDDDDK-tagged Human cells DYKDDDDK
Human ROR1-1815HAF555 Recombinant Human ROR1 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc Gln30-Glu403
Human ROR1-198HAF647 Recombinant Human ROR1 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His
Human ROR1-387HAF647 Recombinant Human ROR1 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc Met1-Glu403, 615
Human ROR1-1815HAF488 Recombinant Human ROR1 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc Gln30-Glu403
Human ROR1-1815HA Recombinant Human ROR1 protein, Fc-tagged, APC labeled HEK293 Fc
Human ROR1-5510H Recombinant Human ROR1 protein, His-tagged Yeast His 30-391aa
Human ROR1-387HF Recombinant Human ROR1 Protein, Fc-tagged, FITC conjugated HEK293 Fc Met1-Glu403, 615
Human ROR1-9879M Active ROR1 protein-coupled magnetic Beads HEK293 Gln 30 - Glu 403
Human ROR1-387HP Recombinant Human ROR1 protein, Fc-tagged, R-PE labeled HEK293 Fc
Human ROR1-140HFL Active Recombinant Full Length Human ROR1 Protein, C-Flag-tagged Mammalian cells Flag
Human ROR1-387HA Recombinant Human ROR1 protein, Fc-tagged, APC labeled HEK293 Fc
Human ROR1-428H Recombinant Human ROR1 Protein, His-tagged HEK293 His 937
Human ROR1-1815HAF647 Recombinant Human ROR1 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc Gln30-Glu403
Human ROR1-1905H-B Recombinant Human ROR1 Protein Pre-coupled Magnetic Beads HEK293
Human ROR1-1815HF Recombinant Human ROR1 Protein, Fc-tagged, FITC conjugated HEK293 Fc Gln30-Glu403
Human ROR1-2818H Recombinant Human ROR1 protein(11-400 aa), C-His-tagged HEK293 C-His 11-400 aa
Human ROR1-198HF Recombinant Human ROR1 Protein, His-tagged, FITC conjugated HEK293 His
Human ROR1-1905H Recombinant Human ROR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ROR1-5876H Recombinant Human ROR1 Protein (Gln30-Tyr406), C-His tagged Mammalian cells C-His Gln30-Tyr406
Human ROR1-5877H Recombinant Human ROR1 Protein (Asp250-Asn364), N-His tagged E.coli N-His Asp250-Asn364
Mouse Ror1-193M Recombinant Mouse Ror1 protein, His-tagged HEK293 His Gln30-Glu403
Mouse Ror1-192M Recombinant Mouse Ror1 protein, Fc-tagged HEK293 human/IgG1/Fc Gln30-Glu403
Mouse ROR1-14377M Recombinant Mouse ROR1 Protein Mammalian Cell His
Mouse Ror1-431M Recombinant Mouse Ror1 Protein, Fc-tagged HEK293 Fc 937
Mouse Ror1-192MAF488 Recombinant Mouse Ror1 Protein, hFc-tagged, Alexa Fluor 488 conjugated HEK293 hFc Gln30-Glu403
Mouse Ror1-513M Recombinant Mouse Ror1 Protein, His-tagged E.coli His Leu470~Lys707
Mouse Ror1-430M Recombinant Mouse Ror1 Protein, His-tagged HEK293 His 937
Mouse ROR1-0659M Recombinant Mouse ROR1 protein, Fc-tagged HEK293 Fc Gln30-Glu403
Mouse Ror1-5572M Recombinant Mouse Ror1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Ror1-192MAF555 Recombinant Mouse Ror1 Protein, hFc-tagged, Alexa Fluor 555 conjugated HEK293 hFc Gln30-Glu403
Mouse Ror1-192MP Recombinant Mouse Ror1 protein, Fc-tagged, R-PE labeled HEK293 Fc
Mouse ROR1-7706M-B Recombinant Mouse ROR1 Protein Pre-coupled Magnetic Beads HEK293
Mouse ROR1-7706M Recombinant Mouse ROR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Ror1-194M Recombinant Mouse Ror1(Gln30-Tyr406) protein, His-tagged HEK293 His Gln30-Tyr406
Mouse Ror1-01M Active Recombinant Mouse Ror1 Protein (Gln30-Glu403), C-mFc-tagged NS0 C-mFc
Mouse Ror1-192MF Recombinant Mouse Ror1 Protein, hFc-tagged, FITC conjugated HEK293 hFc Gln30-Glu403
Mouse Ror1-192MAF647 Recombinant Mouse Ror1 Protein, hFc-tagged, Alexa Fluor 647 conjugated HEK293 hFc Gln30-Glu403
Mouse Ror1-192MA Recombinant Mouse Ror1 protein, Fc-tagged, APC labeled HEK293 Fc
Rat Ror1-1816R Active Recombinant Rat Ror1 protein, His-tagged HEK293 His Gln 30 - Glu 403
Rat ROR1-432R Recombinant Rat ROR1 Protein, His-tagged HEK293 His Full
Human / Cynomolgus / Rhesus macaque ROR1-0656H Active Recombinant Human / Cynomolgus / Rhesus macaque ROR1 protein, mFc-tagged HEK293 mFc Gln30-Glu403
Human / Cynomolgus / Rhesus macaque ROR1-0658H Active Recombinant Human / Cynomolgus / Rhesus macaque ROR1 protein, His-tagged HEK293 His Glu39-Gly151
Human / Cynomolgus / Rhesus macaque ROR1-0657H Recombinant Human / Cynomolgus / Rhesus macaque ROR1 protein, His-tagged HEK293 His Glu165-Asp305
Chicken ROR1-6078C Recombinant Chicken ROR1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

ROR1 involved in several pathways and played different roles in them. We selected most pathways ROR1 participated on our site, such as Beta-catenin independent WNT signaling, Nuclear Receptors, PCP/CE pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ROR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Beta-catenin independent WNT signalingAP2A1;PRICKLE1B;DVL1;CLTC;AP2S1;AGO1;CLTB;RYK;CLTA
Nuclear ReceptorsNR2F1A;NR4A2A;ROR1;NR2F1;VDRB;NR1I2;RARG;NR1D2B;RORAA
PCP/CE pathwayRYK;ROR1;PRICKLE1B;PRICKLE1;ROR2
Signal TransductionMDKA;EMR4;THBS3B;LGR5;GAS8;OTULIN;ACVR1C;PRKCHB;PENKB
Signaling by WntRSPO3;CBY1;TNKS;ROR2;RSPO1;RSPO4;ASH2L;SOX32;RBBP5
WNT5A-dependent internalization of FZD2, FZD5 and ROR2ROR1;ROR2

ROR1 has several biochemical functions, for example, ATP binding, Wnt-protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ROR1 itself. We selected most functions ROR1 had, and list some proteins which have the same functions with ROR1. You can find most of the proteins on our site.

Function Related Protein
ATP bindingIP6K2;PKN2;SPO11;PRKACG;P2RX2;LATS1;ADCY7;STK16;TRIT1
Wnt-protein bindingGPR177;FZD3A;FZD3;CTHRC1;FZD1;SZL;SFRP4;SFRP1B;ROR1
protein bindingMECP2;MRPS31;FAAH;CCDC43;GBAS;SHANK3;BFAR;OAS3;ZEB1
transmembrane receptor protein tyrosine kinase activityFGFR1A;TEK;EPHB3A;INSRA;NTRK3A;TYRO3;KIT;LTK;NPTN

ROR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ROR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ROR1.

SRC; Src; EGFR

Research Area

Related articles

Zhang, SP; Cui, B; et al. Ovarian cancer stem cells express ROR1, which can be targeted for anti-cancer-stem-cell therapy. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:17266-17271(2014).
Hojjat-Farsangi, M; Moshfegh, A; et al. The receptor tyrosine kinase ROR1-An oncofetal antigen for targeted cancer therapy. SEMINARS IN CANCER BIOLOGY 29:21-31(2014).
  • Q&As
  • Reviews

Q&As (4)

Ask a question
What is the expression level of ROR1 in normal tissues. 11/28/2022

ROR1 is barely expressed in normal, differentiated and mature tissues, but is highly expressed in tumor tissues.

What are the effects of inhibiting ROR1 expression? 07/14/2022

Inhibit the expression of ROR1 can reduce the proliferation and migration ability of tumor cells.

What biological processes is ROR1 involved in? 12/26/2021

ROR1 is involved in the regulation of cell metabolism, proliferation, apoptosis, and differentiation.

What diseases is ROR1 involved in? 03/01/2021

ROR1 is involved in the study of breast, lung and ovarian cancers.

Customer Reviews (3)

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Reviews
10/18/2022

    Customer service promptly feedback my requests, technical staff timely solve the problems that arise.

    08/13/2022

      Excellent after-sales service, solving many experimental problems.

      04/12/2021

        Fast and timely shipment helped me to get satisfactory experimental results in short time.

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