Recombinant Human TPBG Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: TPBG-271H
• Product Overview: TPBG MS Standard C13 and N15-labeled recombinant protein (NP_006661) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009]
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 45.9 kDa
• AA Sequence: MPGGCSRGPAAGDGRLRLARLALVL LGWVSSSSPTSSASSFSSSAPFLAS AVSAQPPLPDQCPALCECSEAARTV KCVNRNLTEVPTDLPAYVRNLFLTG NQLAVLPAGAFARRPPLAELAALNL SGSRLDEVRAGAFEHLPSLRQLDLS HNPLADLSPFAFSGSNASVSAPSPL VELILNHIVPPEDERQNRSFEGMVV AALLAGRALQGLRRLELASNHFLYL PRDVLAQLPSLRHLDLSNNSLVSLT YVSFRNLTHLESLHLEDNALKVLHN GTLAELQGLPHIRVFLDNNPWVCDC HMADMVTWLKETEVVQGKDRLTCAY PEKMRNRVLLELNSADLDCDPILPP SLQTSYVFLGIVLALIGAIFLLVLY LNRKGIKKWMHNIRDACRDHMEGYH YRYEINADPRLTNLSSNSDVTRTRP LEQKLISEEDLAANDILDYKDDDDK V
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TPBG trophoblast glycoprotein [ Homo sapiens (human) ]
• Official Symbol: TPBG
• Synonyms: TPBG; trophoblast glycoprotein; 5T4; 5T4 AG; 5T4 oncofetal antigen; 5T4 oncotrophoblast glycoprotein; 5T4 oncofetal trophoblast glycoprotein; M6P1; 5T4AG
• Gene ID: 7162
• mRNA Refseq: NM_006670
• Protein Refseq: NP_006661
• MIM: 190920
• UniProt ID: Q13641