TPBG

  • Official Full Name

    trophoblast glycoprotein

  • Overview

    This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5 UTR results in multiple transcript variants that encode the same protein.
  • Synonyms

    5T4; trophoblast glycoprotein; 5T4 oncotrophoblast glycoprotein; M6P1; 5T4AG; TPBG; trophoblast glycoprotein; 5T4 oncofetal antigen; 5T4 oncotrophoblast glycoprotein; 5T4 oncofetal trophoblast glycoprotein; 5T4-AG; Naptumomab estafenatox; 676258-98-3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus
  • Cynomolgus monkey
  • Cynomolgus Monkey
  • Cynomolgus/Rhesus macaque
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • CHO cells
  • E.coli
  • HEK293
  • HEK293F
  • HEK293T
  • Human Cell
  • Mamanlian cells
  • Mammalian Cell
  • Yeast
  • C
  • Avi
  • 6His
  • hFc
  • Myc
  • DDK
  • Fc
  • Flag
  • His
  • His (Fc)
  • His\Avi
  • His|Myc
  • His|SUMO
  • mFc
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TPBG-051H Active Recombinant Human TPBG protein, His/Avi-tagged, Biotinylated CHO cells His/Avi Ser31-Ser355
Human TPBG-656H Recombinant Human TPBG Protein, His-tagged E.coli His Ser32~Ser351
Human TPBG-190H Recombinant Human TPBG protein, MYC/DDK-tagged HEK293 Myc/DDK
Human TPBG-852HCL Recombinant Human TPBG 293 Cell Lysate HEK293 N/A
Human TPBG-30H Recombinant Human TPBG(Ser32-Ser355) Protein, C-mFc-tagged HEK293 mFc
Human TPBG-6499H Recombinant Human TPBG Protein (Ser32-Ser355), N-His tagged E.coli N-His Ser32-Ser355
Human TPBG-32H Active Recombinant Human TPBG Protein, Fc-tagged HEK293 Fc Ser 32 - Ser 355
Human TPBG-375H Active Recombinant Human TPBG protein, His-Avi-tagged HEK293 His-Avi Ser 32 - Ser 355
Human TPBG-33H Active Recombinant Human TPBG protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Ser 32 - Ser 355
Human TPBG-271H Recombinant Human TPBG Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human TPBG-559H Recombinant Human TPBG Protein, His-tagged HEK293 His Asp60-Asp345
Human TPBG-4992HFL Recombinant Full Length Human TPBG protein, Flag-tagged Mamanlian cells Flag
Human TPBG-2366H Recombinant Human TPBG protein, His-tagged HEK293 His Met1-Ser355
Human TPBG-26H Recombinant Human TPBG Protein, C-Avi-6His tagged, Biotinylated Human Cell C-Avi-6His Ser32-Ser355
Human TPBG-198H Recombinant Human TPBG Protein, His\Avi-tagged Human Cell His\Avi
Mouse TPBG-17246M Recombinant Mouse TPBG Protein Mammalian Cell His
Mouse Tpbg-657M Recombinant Mouse Tpbg Protein, His-tagged E.coli His Pro34~Gln356
Mouse TPBG-9528M Recombinant Mouse TPBG Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse TPBG-9528M-B Recombinant Mouse TPBG Protein Pre-coupled Magnetic Beads HEK293
Mouse TPBG-16M Recombinant Mouse TPBG(Ser32-Ser361) Protein, C-6*His-tagged HEK293 His
Mouse Tpbg-469M Recombinant Mouse Tpbg Protein, His-tagged HEK293F N-His Ser32-Ser361
Mouse Tpbg-6590M Recombinant Mouse Tpbg Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse TPBG-1351M Recombinant Mouse TPBG protein(Met1-Ser361), hFc-tagged HEK293 C-hFc Met1-Ser361
Rat TPBG-6235R Recombinant Rat TPBG Protein Mammalian Cell His
Rat TPBG-5892R Recombinant Rat TPBG Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat TPBG-5892R-B Recombinant Rat TPBG Protein Pre-coupled Magnetic Beads HEK293
Rat TPBG-1765R Recombinant Rat TPBG Protein (32-361 aa), His-SUMO-tagged E.coli His/SUMO 32-361 aa
Cynomolgus TPBG-2201C Recombinant Cynomolgus TPBG protein, His-tagged HEK293 His Thr 35 - Ser 355
Cynomolgus Monkey TPBG-2521C Recombinant Cynomolgus Monkey TPBG Protein (35-355 aa), His-tagged Yeast His 35-355 aa
Cynomolgus monkey TPBG-3610C Recombinant Cynomolgus monkey TPBG protein, His&Myc-tagged E.coli His&Myc 35-355aa
Cynomolgus monkey TPBG-5075C Recombinant Cynomolgus monkey TPBG protein, His&Myc-tagged HEK293 His&Myc 35-355aa
Cynomolgus Monkey TPBG-2548C Recombinant Cynomolgus Monkey TPBG Protein (35-355 aa), His-Myc-tagged E.coli His/Myc 35-355 aa
Cynomolgus/Rhesus macaque TPBG-2520C Active Recombinant Cynomolgus/Rhesus macaque TPBG(Thr35-Ser355) Protein, His-tagged HEK293 His Thr 35 - Ser 355
Rhesus Macaque TPBG-4915R Recombinant Rhesus monkey TPBG Protein, His-tagged Mammalian Cell His
Rhesus Macaque TPBG-4729R-B Recombinant Rhesus Macaque TPBG Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque TPBG-4729R Recombinant Rhesus Macaque TPBG Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

TPBG involved in several pathways and played different roles in them. We selected most pathways TPBG participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TPBG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

TPBG has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by TPBG itself. We selected most functions TPBG had, and list some proteins which have the same functions with TPBG. You can find most of the proteins on our site.

Function Related Protein

TPBG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TPBG here. Most of them are supplied by our site. Hope this information will be useful for your research of TPBG.

GIPC1; cona_canen

  • Q&As
  • Reviews

Q&As (7)

Ask a question
What is the significance of TPBG in cancer diagnosis or prognosis? 01/23/2022

Elevated TPBG levels can serve as a biomarker and may correlate with poor prognosis in some cancers.

Are there any known post-translational modifications of TPBG, and what are their effects? 07/08/2021

While the post-translational modifications of TPBG are not fully elucidated, they could affect its localization, stability, and interactions with other proteins.

What known proteins interact with TPBG, influencing its function? 03/15/2021

Specific interacting partners of TPBG that significantly influence its function are still under investigation.

How does TPBG expression change in cancerous cells? 03/01/2021

TPBG expression is often upregulated in various types of cancer cells.

How does TPBG contribute to the immune evasion of cancer cells? 06/27/2020

TPBG might contribute to immune evasion by interacting with immune cells and modulating immune responses.

What is the primary biological role of TPBG in normal cells? 02/09/2020

TPBG plays roles in cell adhesion, migration, and proliferation in normal cells.

What potential therapeutic interventions could target TPBG? 07/14/2019

Targeting TPBG could provide a therapeutic avenue, particularly in cancers where it is overexpressed, potentially improving immune response and treatment outcomes.

Customer Reviews (3)

Write a review
Reviews
09/01/2022

    Reliable and reproducible results.

    04/28/2021

      Worked well for Western blot.

      06/17/2018

        Great for research purposes.

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