Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Rat TPBG Protein (32-361 aa), His-SUMO-tagged

Cat.No. : TPBG-1765R
Product Overview : Recombinant Rat TPBG Protein (32-361 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Protein Description: Full Length of Mature Protein.
  • Specification
  • Gene Information
  • Related Products
Description : May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization.
Source : E. coli
Species : Rat
Tag : His-SUMO
Form : Tris-based buffer,50% glycerol
Molecular Mass : 51.8 kDa
Protein length : 32-361 aa
AA Sequence : SAPSSSLPSSSTSPAAFLASGSAQP PPAERCPAACECSEAARTVKCVNRN LLEVPADLPPYVRNLFLTGNQMTVL PAGAFARQPPLADLAVLNLSGNHLK EVGAGAFEHLPGLRRLDLSHNPLTN LSAFTFAGSNVSVSTPSPLLELILN HIVPPEDQRQNGSFEGMVAFEGMVA AALRSGLALRGLHHLELASNHFLYL PRDLLDQLPSLKHLDLRNNSLVSLT YASFRNLTHLESLHLEDNALKVLHN STLAEWQGLAHVRVFLDNNPWVCDC YMADMVSWLKETEVVPDKARLTCAF PEKMRNRGLLDLTSSDLDCDATLPQ SLQTS
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name : Tpbg trophoblast glycoprotein [ Rattus norvegicus ]
Official Symbol : TPBG
Synonyms : TPBG; trophoblast glycoprotein; 5T4; MGC93332;
Gene ID : 83684
mRNA Refseq : NM_031807
Protein Refseq : NP_113995
UniProt ID : Q5PQV5

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (7)

Ask a question
What is the significance of TPBG in cancer diagnosis or prognosis? 01/23/2022

Elevated TPBG levels can serve as a biomarker and may correlate with poor prognosis in some cancers.

Are there any known post-translational modifications of TPBG, and what are their effects? 07/08/2021

While the post-translational modifications of TPBG are not fully elucidated, they could affect its localization, stability, and interactions with other proteins.

What known proteins interact with TPBG, influencing its function? 03/15/2021

Specific interacting partners of TPBG that significantly influence its function are still under investigation.

How does TPBG expression change in cancerous cells? 03/01/2021

TPBG expression is often upregulated in various types of cancer cells.

How does TPBG contribute to the immune evasion of cancer cells? 06/27/2020

TPBG might contribute to immune evasion by interacting with immune cells and modulating immune responses.

What is the primary biological role of TPBG in normal cells? 02/09/2020

TPBG plays roles in cell adhesion, migration, and proliferation in normal cells.

What potential therapeutic interventions could target TPBG? 07/14/2019

Targeting TPBG could provide a therapeutic avenue, particularly in cancers where it is overexpressed, potentially improving immune response and treatment outcomes.

Customer Reviews (3)

Write a review
Reviews
09/01/2022

    Reliable and reproducible results.

    04/28/2021

      Worked well for Western blot.

      06/17/2018

        Great for research purposes.

        Ask a Question for All TPBG Products

        Required fields are marked with *

        My Review for All TPBG Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends