Recombinant Human TTI2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TTI2-6230H
• Product Overview: C8orf41 MS Standard C13 and N15-labeled recombinant protein (NP_079391) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a regulator of the DNA damage response. The protein is a component of the Triple T complex (TTT) which also includes telomere length regulation protein and TELO2 interacting protein 1. The TTT complex is involved in cellular resistance to DNA damage stresses and may act as a regulator of phosphoinositide-3-kinase-related protein kinase (PIKK) abundance.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 56.9 kDa
• AA Sequence: MELDSALEAPSQEDSNLSEELSHSA FGQAFSKILHCLARPEARRGNVKDA VLKDLGDLIEATEFDRLFEGTGARL RGMPETLGQVAKALEKYAAPSKEEE GGGDGHSEAAEKAAQVGLLFLKLLG KVETAKNSLVGPAWQTGLHHLAGPV YIFAITHSLEQPWTTPRSREVAREV LTSLLQVTECGSVAGFLHGENEDEK GRLSVILGLLKPDLYKESWKNNPAI KHVFSWTLQQVTRPWLSQHLERVLP ASLVISDDYQTENKILGVHCLHHIV LNVPAADLLQYNRAQVLYHAISNHL YTPEHHLIQAVLLCLLDLFPILEKT LHWKGDGARPTTHCDEVLRLILTHM EPEHRLLLRRTYARNLPAFVNRLGI LTVRHLKRLERVIIGYLEVYDGPEE EARLKILETLKLLMQHTWPRVSCRL VVLLKALLKLICDVARDPNLTPESV KSALLQEATDCLILLDRCSQGRVKG LLAKIPQSCEDRKVVNYIRKVQQVS EGAPYNGTTRTRPLEQKLISEEDLA ANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TTI2 TELO2 interacting protein 2 [ Homo sapiens (human) ]
• Official Symbol: TTI2
• Synonyms: TTI2; TELO2 interacting protein 2; C8orf41, chromosome 8 open reading frame 41, Tel2 interacting protein 2 homolog (S. pombe); TELO2-interacting protein 2; FLJ23263; Tel2 interacting protein 2 homolog; C8orf41
• Gene ID: 80185
• mRNA Refseq: NM_025115
• Protein Refseq: NP_079391
• MIM: 614426
• UniProt ID: Q6NXR4