Recombinant Mouse Tti2 Protein, Myc/DDK-tagged

• Cat.No.: Tti2-6719M
• Product Overview: Purified recombinant protein of mouse full-length TELO2 interacting protein 2 (Tti2), transcript variant 1, with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.
• Molecular Mass: 56.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Tti2 TELO2 interacting protein 2 [ Mus musculus (house mouse) ]
• Official Symbol: Tti2
• Synonyms: TTI2; TELO2 interacting protein 2; TELO2-interacting protein 2; MGC28346
• Gene ID: 234138
• mRNA Refseq: NM_001112729
• UniProt ID: Q8BGV4