Recombinant Mouse Peli1 Protein, Myc/DDK-tagged
Cat.No. : | Peli1-4790M |
Product Overview : | Purified recombinant protein of mouse full-length pellino 1 (Peli1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1 allowing subsequent NF-kappa-B activation. Mediates 'Lys-48'-linked polyubiquitination of RIPK3 leading to its subsequent proteasome-dependent degradation; preferentially recognizes and mediates the degradation of the 'Thr-182' phosphorylated form of RIPK3. Negatively regulates necroptosis by reducing RIPK3 expression. Mediates 'Lys-63'-linked ubiquitination of RIPK1. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 46.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Peli1 pellino 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Peli1 |
Synonyms : | Peli1; pellino 1; AA409794; AI586297; D11Ertd676; D11Ertd676e; 2810468L03Rik; A930031K15Rik; E3 ubiquitin-protein ligase pellino homolog 1; RING-type E3 ubiquitin transferase pellino homolog 1; protein pellino homolog 1; EC 2.3.2.27 |
Gene ID : | 67245 |
mRNA Refseq : | NM_023324 |
Protein Refseq : | NP_075813 |
UniProt ID : | Q8C669 |
Products Types
◆ Recombinant Protein | ||
PELI1-3188R | Recombinant Rhesus Macaque PELI1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PELI1-1646H | Recombinant Human PELI1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PELI1-659H | Recombinant Human PELI1 Protein, His&GST-tagged | +Inquiry |
PELI1-1255H | Recombinant Human PELI1 | +Inquiry |
PELI1-1641H | Recombinant Human PELI1, GST-tagged | +Inquiry |
◆ Lysates | ||
PELI1-3304HCL | Recombinant Human PELI1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket