PELI2
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Official Full Name
pellino homolog 2 (Drosophila) -
Overview
Protein pellino homolog 2 is a protein that in humans is encoded by the PELI2 gene. -
Synonyms
PELI2;pellino homolog 2 (Drosophila);pellino (Drosophila) homolog 2;E3 ubiquitin-protein ligase pellino homolog 2;Pellino homolog 2;pellino-2;protein pellino homolog 2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PELI2-1642H | Recombinant Human PELI2, His-tagged | E.coli | Human | His | 281-420aa | |
| PELI2-729Z | Recombinant Zebrafish PELI2 | Mammalian Cells | Zebrafish | His |
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| PELI2-3303HCL | Recombinant Human PELI2 293 Cell Lysate | HEK293 | Human | Non |
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| PELI2-0412H | Recombinant Human PELI2 Protein (F2-D420), Tag Free | E.coli | Human | Non | F2-D420 |
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| PELI2-0413H | Recombinant Human PELI2 Protein (F2-D420), His tagged | E.coli | Human | His | F2-D420 |
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Involved Pathway
PELI2 involved in several pathways and played different roles in them. We selected most pathways PELI2 participated on our site, such as Activated TLR4 signalling,Cytokine Signaling in Immune system,IRAK1 recruits IKK complex, which may be useful for your reference. Also, other proteins which involved in the same pathway with PELI2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation | PELI1,PELI3 |
| Interleukin-1 signaling | PELI3,TNIP2,PELI1,IRAK3,NOD1,IL1RN |
| Activated TLR4 signalling | DUSP3,DUSP4,JUN,NOD1,TAB1,ATF2,MAP3K8,CREB1B,DHX9,TANK |
| MyD88 cascade initiated on plasma membrane | TLR10,CHST13,ALCAMB,S100A12,AGER,DUSP3B,PELI3,PELI1,S100B,DHX9 |
| Cytokine Signaling in Immune system | HERC5,KPNA5,EIF4G2,SOCS3A,SPRED2,FRS2A,NUPL2,TRIM68,TRIM45,IFI6 |
| Innate Immune System | CD300LB,FCN1,BTR12,ART1,CRP,NCKIPSD,IRF2,PPAPDC1A,MGC174155,MB21D1 |
| Immune System | CHST13,CTSO,HCST,CR1,BTR12,LGALS9,AF251705,ABI1B,GBP5,S100A12 |
| IRAK1 recruits IKK complex | PELI1,PELI3 |
Protein Function
PELI2 has several biochemical functions, for example, ligase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PELI2 itself. We selected most functions PELI2 had, and list some proteins which have the same functions with PELI2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ligase activity | RFWD3,UHRF1,TTLL4,MARCH4,RNF144AB,RING1,UBE2F,RNF14,MARCH3,RNF4 |
| protein binding | TDO2,ARHGEF10,HMBOX1,FXR2,LUC7L,HNRNPL,SEPT2,TBX5,LDB3,SPAG8 |
Interacting Protein
PELI2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PELI2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PELI2.
IRAK1;IRAK4;UBA1;UBE2N;UBE2V1;SRPK1;DEAF1;FRYL;FN1;HNRNPK;PICALM;CREB3L3;ERO1L;THAP7;UBQLN4;LTBP3
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