Active Recombinant Human FER(541-end) Protein, N-His-tagged
Cat.No. : | FER-79H |
Product Overview : | N-terminal 6His-tagged, recombinant human Fer amino acids 541–end, expressed by baculovirus in Sf21 insect cells. Purified using Ni2+/NTA agarose. |
- Specification
- Gene Information
- Related Products
Description : | FER (TYK3) is a nuclear and cytoplasmic non-receptor tyrosine kinase and able to affect transcription in the nucleus. FER is expressed predominantly in mature hematopoietic cells of the granulocytic and monocytic lineage, implicated in the regulation of myeloid differentiation. Inhibition of FER may be of benefit for the treatment of myeloid and prostate cancer as well as angiogenesis. |
Source : | Sf21 |
Species : | Human |
Tag : | His |
Protein length : | 541-end |
Form : | 0.319mg/ml of enzyme in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 0.2mM PMSF, 1mM benzamidine, 0.1% 2-mercaptoethanol. 20mM sodium β-glycerophosphate, 10mM sodium fluoride, 0.25mM sodium vanadate. Frozen solution. |
Bio-activity : | 863U/mg, where one unit of Fer, active activity is defined as 1nmol phosphate incorporated into 250μM (KKKSPGEYVNIEFG) per minute at 30 centigrade with a final ATP concentration of 100μM. |
Molecular Mass : | 35.6 kDa |
AA Sequence : | 1 MSYYHHHHHH DYDIPTTENL YFQGAMGSKS GVVLLNPIPK DKKWILSHED VILGELLGKG 61 NFGEVYKGTL KDKTSVAVKT CKEDLPQELK IKFLQEAKIL KQYDHPNIVK LIGVCTQRQP 121 VYIIMELVSG GDFLTFLRRK KDELKLKQLV KFSLDAAAGM LYLESKNCIH RDLAARNCLV 181 GENNVLKISD FGMSRQEDGG VYSSSGLKQI PIKWTAPEAL NYGRYSSESD VWSFGILLWE 241 TFSLGVCPYP GMTNQQAREQ VERGYRMSAP QHCPEDISKI MMKCWDYKPE NRPKFSELQK 301 ELTIIKRKLT |
Purity : | Purity 84.4% by SDS-PAGE and Coomassie blue staining. |
Applications : | Drug Discovery & Development |
Storage : | 6 months at -70 centigrade. |
Handling Advice : | Rapidly thaw the vial under cold water and immediately place on ice. Aliquot unused material into prechilled micro-centrifuge tubes and immediately snap-freeze the vials in liquid nitrogen prior to re-storage at -70 centigrade. |
Use/Stability : | On receipt of material store at -70 centigrade. Unopened reagent is stable for a minimum of 1 year from date of shipment when stored at recommended storage temperature. Avoid repeat freeze/thaw cycles. For maximum recovery of product, centrifuge original vial prior to removing the cap. |
Gene Name : | FER FER tyrosine kinase [ Homo sapiens (human) ] |
Official Symbol : | FER |
Synonyms : | FER; FER tyrosine kinase; TYK3; PPP1R74; p94-Fer |
Gene ID : | 2241 |
mRNA Refseq : | NM_005246.4 |
Protein Refseq : | NP_005237.2 |
MIM : | 176942 |
UniProt ID : | P16591 |
Products Types
◆ Recombinant Protein | ||
FER-4073H | Active Recombinant Human FER Protein, GST/His-tagged | +Inquiry |
FER-1323S | Recombinant Human FER Protein (M1-T822), Tag Free | +Inquiry |
FER-1324S | Recombinant Human FER Protein (M1-T822), GST tagged | +Inquiry |
FER-2084B | Recombinant Bacillus subtilis FER protein, His-tagged | +Inquiry |
FER-1869H | Recombinant Human FER protein, GST-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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