Recombinant Human NFKB Inhibitor Interacting Ras-like 1, His-tagged
Cat.No. : | NKIRAS1-5545H |
Product Overview : | Recombinant humanNKIRAS1 protein, fused to His-tag at N-terminus, was expressed in E. coliand purified by using conventional chromatography. |
- Specification
- Gene Information
- Related Products
Cat. No. : | NKIRAS1-5545H | ||
Description : | NKIRAS1, also knownas NF-kappa-B inhibitor-interacting Ras-like protein 1,belongs to the small GTPase superfamily. NKIRAS1 is atypical Ras-like protein that acts as apotent regulator of NF-kappa-B activity by preventing the degradation ofNF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB ismore resistant to degradation. It may act by blocking phosphorylation ofNFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. Itis unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms blockphosphorylation of NFKBIB. | ||
Form : | Liquid. 20mMTris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT. | ||
Molecular Weight : | 23.8 kDa (212aa),confirmed by MALDI-TOF. | ||
Purity : | > 95%by SDS-PAGE | ||
Concentration : | 0.25 mg/ml(determined by Bradford assay) | ||
Sequences of aminoacids : | MGSSHHHHHH SSGLVPRGSH MGKGCKVVVCGLLSVGKTAI LEQLLYGNHT IGMEDCETME DVYMASVETD RGVKEQLHLY DTRGLQEGVE LPKHYFSFADGFVLVYSVNN LESFQRVELL KKEIDKFKDK KEVAIVVLGN KIDLSEQRQV DAEVAQQWAK SEKVRLWEVTVTDRKTLIEP FTLLASKLSQ PQSKSSFPLP GRKNKGNSNS EN | ||
Storage : | Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles. | ||
OfficialSymbol : | NKIRAS1 | ||
nullValue_other : |
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Gene Name : | NKIRAS1NFKB inhibitor interacting Ras-like 1 [ Homo sapiens ] |
Synonyms : | NKIRAS1; NFKBinhibitor interacting Ras-like 1; KBRAS1; kappaB-Ras1; NF-kappa-Binhibitor-interacting Ras-like protein 1; kappa B-ras 1; kappa B-Ras protein1; I-kappa-B-interacting Ras-like protein 1; OTTHUMP00000208334; OTTHUMP00000208335;OTTHUMP00000208336; OTTHUMP00000208337; OTTHUMP00000208338; OTTHUMP00000208339;OTTHUMP00000214794; OTTHUMP00000214795 |
Gene ID : | 28512 |
mRNA Refseq : | NM_020345 |
Protein Refseq : | NP_065078 |
MIM : | 604496 |
UniProt ID : | Q9YNS0 |
Chromosome Location : | 3p24.2 |
Products Types
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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