Active Recombinant Human Thrombopoietin
Cat.No. : | THPO-27H |
Product Overview : | Recombinant Human THPO (Ser22-Gly349) was produced in HEK293 Cells. |
- Specification
- Gene Information
- Related Products
Cat. No. : | THPO-27H |
Description : | Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternate splicing results in multiple transcript variants of this gene. |
Source : | HEK293 Cells |
Molecular Mass : | 37.4 kDa |
Formulation : | Lyophilized from 0.22 μm filtered solution in 50mM Tris 150mM NaCl pH 7.0. Normally Mannitol or Trehalose are added as protectants before lyophilization. |
Purity : | >95% as determined by SDS-PAGE. |
Endotoxin : | Less than 1.0 EU per μg of the rhTPO by the LAL method. |
Bioactivity : | The bio-activity was determined by dose-dependent stimulation of the proliferation of MO7e cells. The ED50<1ng/ml, corresponding to a specific activity of >1X106 Unit/mg. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4oC-8oC); After reconstitution under sterile conditions for 1 month (4oC-8oC) or 3 months (-20oC to -70oC). |
OfficialSymbol : | THPO |
Gene Name : | THPO thrombopoietin [ Homo sapiens ] |
Synonyms : | THPO; thrombopoietin; ML; TPO; MGDF; MKCSF; MPLLG; MGC163194; MPL ligand; c-mpl ligand; thrombopoietin nirs variant 1; megakaryocyte stimulating factor; megakaryocyte colony-stimulating factor; megakaryocyte growth and development factor; myeloproliferative leukemia virus oncogene ligand |
Gene ID : | 7066 |
mRNA Refseq : | NM_000460 |
Protein Refseq : | NP_000451 |
MIM : | 600044 |
UniProt ID : | P40225 |
Chromosome Location : | 3q27 |
Pathway : | Hematopoietic cell lineage; Platelet Aggregation (Plug Formation); Platelet activation, signaling and aggregation |
Function : | cytokine activity; growth factor activity; hormone activity |
Products Types
◆ Recombinant Protein | ||
THPO-4490H | Recombinant Human THPO Protein, His (Fc)-Avi-tagged | +Inquiry |
Thpo-6417M | Active Recombinant Mouse Thpo Protein | +Inquiry |
THPO-2753H | Recombinant Human THPO protein(22-353 aa), N-SUMO & C-His-tagged | +Inquiry |
Thpo-6418M | Active Recombinant Mouse Thpo Protein | +Inquiry |
Thpo-111M | Recombinant Mouse Thpo Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
THPO-2832HCL | Recombinant Human THPO cell lysate | +Inquiry |
THPO-2831MCL | Recombinant Mouse THPO cell lysate | +Inquiry |
THPO-001HCL | Recombinant Human THPO cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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