thpo
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  • Official Full Name
  • thrombopoietin
  • Background
  • Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5 UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent. [provided by RefSeq, Feb 2014]
  • Synonyms
  • THPO; thrombopoietin; ML; TPO; MGDF; MKCSF; MPLLG; THCYT1; MPL ligand; c-mpl ligand; prepro-thrombopoietin; megakaryocyte stimulating factor; megakaryocyte colony-stimulating factor; megakaryocyte growth and development factor; myeloproliferative leukemia virus oncogene ligand;
Cat.#:Thpo-895MTag:
Source (Host):CHOSpecies:Mouse
Product nameRecombinant Mouse Thpo Protein
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Cat.#:Thpo-891RTag:
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Thpo Protein
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Cat.#:THPO-1533HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human Thrombopoietin
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Cat.#:Thpo-1531MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Thrombopoietin
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Cat.#:THPO-269HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Thrombopoietin
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Cat.#:THPO-175HTag:N/A
Source (Host):Sf 21 Insect cellsSpecies:Human
Product nameRecombinant Human Thrombopoietin
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Cat.#:THPO-176HTag:N/A
Source (Host):NS0Species:Human
Product nameRecombinant Human Thrombopoietin
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Cat.#:THPO-216HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human THPO Protein, His-tagged
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Cat.#:THPO-26HTag:N/A
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Thrombopoietin
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Cat.#:THPO-27HTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human Thrombopoietin
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Cat.#:THPO-29518THTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human THPO
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Cat.#:THPO-29520THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human THPO
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Cat.#:THPO-573HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human THPO protein, His & GST-tagged
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Cat.#:THPO-80HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human THPO, His-tagged
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Cat.#:THPO-81HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human THPO, Fc-tagged
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Cat.#:THPO-82HTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human Thrombopoietin
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Cat.#:THPO-861HTag:His
Source (Host):CHOSpecies:Human
Product nameRecombinant Human THPO, His tagged
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Cat.#:THPO-98HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human Thrombopoietin, His-tagged
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Cat.#:THPO-99HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human THPO protein, His-tagged
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Cat.#:Thpo-177MTag:N/A
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Thrombopoietin
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Cat.#:Thpo-1782MTag:Fc
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Thrombopoietin, Fc Chimera
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Cat.#:Thpo-94MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse thrombopoietin
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Cat.#:Thpo-97MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Thpo, His tagged
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Cat.#:Thpo-575RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Thpo protein, His & T7-tagged
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Cat.#:THPO-6057RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat THPO Protein
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Cat.#:THPO-1163CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus THPO Protein, His-tagged
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Cat.#:THPO-1175CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken THPO
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Cat.#:THPO-7258ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish THPO
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Cat.#:THPO-001HCLTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human THPO cell lysate
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Cat.#:THPO-2832HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human THPO cell lysate
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Cat.#:THPO-2831MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse THPO cell lysate
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Cat.#:THPO-2273CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus THPO cell lysate
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Cat.#:THPO-13HTag:
Source (Host):Species:Human
Product nameRecombinant Human Thrombopoietin Reference standard
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Cat.#:THPO-P02HTag:Fc
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human THPO, Fc-tagged therapeutic protein
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THPO Related Articles

Kuter, DJ; et al. Milestones in understanding platelet production: a historical overview. BRITISH JOURNAL OF HAEMATOLOGY 165:248-258(2014).
Arai, F; Yoshihara, H; et al. Niche Regulation of Hematopoietic Stem Cells in the Endosteum The Role of Thrombopoietin/Mp1 Signaling in the Maintenance of Quiescent Hematopoietic Stem Cells. HEMATOPOIETIC STEM CELLS VII 1176:36-46(2009).