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Recombinant Human HSPB1, GST-tagged

Cat.No.: HSPB1-13990H
Product Overview: Recombinant Human HSPB1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).
Source: E.coli
Species: Human
Tag: GST
Protein length: 1-205a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: HSPB1 heat shock 27kDa protein 1 [ Homo sapiens ]
Official Symbol: HSPB1
Synonyms: HSPB1; heat shock 27kDa protein 1; heat shock 27kD protein 1; heat shock protein beta-1; Hs.76067; Hsp25; HSP27; HSP28; HSP 27; 28 kDa heat shock protein; heat shock 27 kDa protein; stress-responsive protein 27; estrogen-regulated 24 kDa protein; CMT2F; HMN2B; SRP27; HS.76067; DKFZp586P1322;
Gene ID: 3315
mRNA Refseq: NM_001540
Protein Refseq: NP_001531
MIM: 602195
UniProt ID: P04792
Chromosome Location: 7q11.23
Pathway: Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Destabilization of mRNA by AUF1 (hnRNP D0), organism-specific biosystem; FAS pathway and Stress induction of HSP regulation, organism-specific biosystem; Gene Expression, organism-specific biosystem; IL-3 Signaling Pathway, organism-specific biosystem; IL-6 Signaling Pathway, organism-specific biosystem;
Function: protein binding; protein kinase C binding; protein kinase C delta binding; protein kinase C inhibitor activity; protein kinase binding; ubiquitin binding;

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