HSPB1

  • Official Full Name

    heat shock 27kDa protein 1

  • Overview

    Heat shock proteins (HSP) are a class of functionally related proteins whose expression is increased when cells are exposed to elevated temperatures or other stress. This increase in expression is transcriptionally regulated. The dramatic upregulation of the heat shock proteins is a key part of theheat shock response and is induced primarily by heat shock factor (HSF). HSPs are found in virtually all living organisms, from bacteria to humans.
  • Synonyms

    Heat shock protein; HSP; THR-PHE-GLY-LEU-GLN-LEU-GLU-LEU-THR; H-THR-PHE-GLY-LEU-GLN-LEU-GLU-LEU-THR-OH; HEAT SHOCK PROTEIN, 65 KD, MYCOBACTERIUM BOVIS BCG, FRAGMENT 180-188; HEAT SHOCK PROTEIN, 65KD, MYCOBACTERIUM BOVIS BCG; SNP nonapeptide;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Cattle
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293F
  • HEK293T
  • In Vitro Cell Free System
  • Mamanlian cells
  • Mammalian Cell
  • Mouse
  • Rabbit
  • S.frugiperda
  • Wheat Germ
  • C
  • His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|MBP
  • His|T7
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HSPB1-320H Recombinant Human Heat Shock 27 kDa Protein 1 E.coli His
Human HSPB1-5114H Recombinant Human HSPB1 Protein, GST-tagged Wheat Germ GST
Human HSPB1-4853H Recombinant Human Heat Shock 27kDa Protein 1, GST-tagged E.coli GST
Human HSPB1-4923H Recombinant Human Heat Shock 27kDa Protein 1 E.coli N/A
Human HSPB1-1825H Recombinant Human Heat Shock Protein Beta-1, His tagged E.coli His
Human HSPB1-13990H Recombinant Human HSPB1, GST-tagged E.coli GST 1-205a.a.
Human HSPB1-27737TH Recombinant Human HSPB1 E.coli N/A
Human HSPB1-2651H Recombinant Human Heat Shock 27kDa Protein 1, His-tagged S.frugiperda His
Human HSPB1-273H Recombinant Human HSPB1 protein, His/MBP-tagged E.coli His/MBP
Human HSPB1-849H Recombinant Human HSPB1 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human HSPB1-1553H Recombinant Human HSPB1 protein E.coli N/A
Human HSPB1-1554H Recombinant Human HSPB1 protein(Met1-Lys205), His-tagged E.coli C-His Met1-Lys205
Human HSPB1-5351HCL Recombinant Human HSPB1 293 Cell Lysate HEK293 N/A
Human HSPB1-070H Recombinant Human HSPB1 Protein, His-tagged E.coli His 2-205
Human CAB11554MH Mouse Anti-Human HSP27 Monoclonal Antibody Mouse N/A
Human HSPB1-017H Recombinant Human HSPB1 Protein, His-tagged E.coli His 2-205
Human HSPB1-2509HFL Recombinant Full Length Human HSPB1 protein, Flag-tagged Mamanlian cells Flag
Human HSPB1-971H Recombinant Human HSPB1 Protein, His-tagged HEK293F N-His Thr2-Lys205
Human HSPB1-2987H Recombinant Human HSPB1 Protein (Met1-Lys205), His tagged E.coli His Met1-Lys205
Human HSPB1-5358H Recombinant Human HSPB1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HSPB1-3964HF Recombinant Full Length Human HSPB1 Protein, GST-tagged In Vitro Cell Free System GST 205 amino acids
Human CAB11555RH Rabbit Anti-Human HSP27 / HSPB1 Monoclonal Antibody Rabbit N/A
Human HSPB1-046H Recombinant Human HSPB1 Protein E.coli 205
Human HSPB1-2549H Recombinant Human HSPB1 protein(61-200 aa), C-His-tagged E.coli C-His 61-200 aa
Mouse Hspb1-814M Recombinant Mouse Hspb1 protein, His-tagged E.coli His Met1~Lys209 (Accession # P14602)
Mouse HSPB1-7913M Recombinant Mouse HSPB1 Protein Mammalian Cell His
Mouse HSPB1-4360M Recombinant Mouse HSPB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HSPB1-4360M-B Recombinant Mouse HSPB1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Hspb1-1187M Recombinant Mouse Hspb1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat HSPB1-2950R Recombinant Rat HSPB1 Protein Mammalian Cell His
Rat HSPB1-2605R Recombinant Rat HSPB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HSPB1-2605R-B Recombinant Rat HSPB1 Protein Pre-coupled Magnetic Beads HEK293
Cattle HSPB1-813C Recombinant Cattle HSPB1 protein, His & T7-tagged E.coli His/T7 Met1~Lys201 (Accession # Q3T149)
Rhesus Macaque HSPB1-2167R Recombinant Rhesus monkey HSPB1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque HSPB1-1988R Recombinant Rhesus Macaque HSPB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HSPB1-1988R-B Recombinant Rhesus Macaque HSPB1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish HSPB1-1905Z Recombinant Zebrafish HSPB1 Mammalian Cell His
Chicken HSPB1-6842C Recombinant Chicken HSPB1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

HSPB1 involved in several pathways and played different roles in them. We selected most pathways HSPB1 participated on our site, such as MAPK signaling pathway, VEGF signaling pathway, Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HSPB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwayCACNB3;PDGFA;MAP3K4;MAP2K7;PLA2G4F;PTPRR;CACNG6A;RAC1;CACNB4A
VEGF signaling pathwayHRAS;AKT1;AKT2;PLA2G4D;PIK3R5;KRAS;PIK3R3A;MAP2K2A;HRASB
AmoebiasisRAB7B;PLCB3;IL-8;MUC2;SERPINB6B;LAMA5;COL5A1;PIK3CG;RAB5C
Epstein-Barr virus infectionPSMD6;GTF2E1;NEDD4;MAPK9;GSK3B;HSPA2;STAT3;CR2;YWHAG

HSPB1 has several biochemical functions, for example, identical protein binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HSPB1 itself. We selected most functions HSPB1 had, and list some proteins which have the same functions with HSPB1. You can find most of the proteins on our site.

Function Related Protein
identical protein bindingSIAH1A;KIRRELA;BAIAP2;CAV1;SP100;LEPR;IGF2R;DPP9;TARDBP
poly(A) RNA bindingCDK5R2;DNAJC2;MRPL28;EIF1AX;LSM8;FASTKD5;FAM50A;RBMX2;AGO3
protein bindingRORB;ZFP746;SNAPC5;NFU1;NEU4;SERP1;EEF1A2;COPS3;CBS
protein kinase C bindingDSP;HAND2;HDAC9;IRS1;TWF2;MARCKS;PICK1;SDPRA;ADAM9
protein kinase C inhibitor activitySFN;YWHAG;HSPB1
protein kinase bindingSTK11IP;SPDYE2;AP2A2;SPAG16;PIH1D1;CAMK2N2;IBTK;CCNL1A;ADAM10
ubiquitin bindingD17WSU92E;C6orf106;UBAP1;OTUB1;TRIM32;UBXN11;BCL10;CXCR4;UCHL3

HSPB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSPB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HSPB1.

BAG3; CRYAB; TP53; YWHAZ; EGFR

Research Area

Related articles

Ding, YB; Yang, M; et al. iTRAQ-based quantitative proteomic analysis of cervical cancer. INTERNATIONAL JOURNAL OF ONCOLOGY 46:1748-1758(2015).
Gulyas, G; Czegledi, L; et al. PROTEOMIC ANALYSIS OF SKELETAL MUSCLE AT DIFFERENT LIVE WEIGHTS IN CHAROLAIS BULLS. ACTA ALIMENTARIA 44:132-138(2015).
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