Recombinant Human ICAM1, HIgG1 Fc-tagged

Cat.No.: ICAM1-101H
Product Overview: The extracellular domain of human CD54 (AAH15969.1) (Met1-Glu480)(Gln348Lys) is fused to the N-terminus of the Fc region of human IgG1 was expressed in CHO cell.
Description: This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor
Source: CHO cells
Species: Human
Tag: HIgG1 Fc-tagged
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Measured by the ability of the immobilized protein to support the adhesion of PMA-stimulated HSB2 human peripheral blood acute lymphoblastic leukemia cells.
AA Sequence: (Met1-Glu480)(Gln348Lys)
Endotoxin: <0.06 eu/μg as determined by lal test.>
Purity: >98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: ICAM1 intercellular adhesion molecule 1 [ Homo sapiens ]
Official Symbol: ICAM1
Synonyms: ICAM1; intercellular adhesion molecule 1; BB2; CD54; human rhinovirus receptor; ICAM-1; cell surface glycoprotein P3.58; major group rhinovirus receptor; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; P3.58;
Gene ID: 3383
mRNA Refseq: NM_000201
Protein Refseq: NP_000192
MIM: 147840
UniProt ID: P05362
Chromosome Location: 19p13.3-p13.2
Pathway: Adaptive Immune System, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Glucocorticoid receptor regulatory network, organism-specific biosystem;
Function: cell surface binding; integrin binding; protein binding; receptor activity; transmembrane signaling receptor activity;

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.