Recombinant Human TCN1

• Cat.No.: TCN1-27949TH
• Product Overview: Recombinant fragment corresponding to aa 1-424 Human TCN1 with N-terminal proprietary tag.Mol Wt 72.27 kDa inclusive of tag.

Specification

• Description: This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells.
• Protein length: 424 amino acids
• Molecular Weight: 72.270kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Neutrophil granule protein.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MRQSHQLPLVGLLLFSFIPSQLCEICEVSEENYIRLKPLL NTMIQSNYNRGTSAVNVVLSLKLVGIQIQTLMQKMIQQIK YNVKSRLSDVSSGELALIILALGVCRNAEENLIYDYHLID KLENKFQAEIENMEAHNGTPLTNYYQLSLDVLALCLFNGN YSTAEVVNHFTPENKNYYFGSQFSVDTGAMAVLALTCVKK SLINGQIKADEGSLKNISIYTKSLVEKILSEKKENGLIGN TFSTGEAMQALFVSSDYYNENDWNCRQTLNTVLTEISQGA FSNPNAAAQVLPALMGKTFLDINKDSSCVPASGNFNISAD EPITVTPPDSQSYISVDYSVRINETYFTNVAVLNGSVFLS VMEKAQKMNDTIFGFTMEERSWGPYITCIQGLCANNNDRT YWELLSGGEPLSQGAGSYVVRNG
• Sequence Similarities: Belongs to the eukaryotic cobalamin transport proteins family.

Gene Information

• Gene Name: TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) [ Homo sapiens ]
• Official Symbol: TCN1
• Synonyms: TCN1; transcobalamin I (vitamin B12 binding protein, R binder family); transcobalamin-1; haptocorin; haptocorrin; TC1; TCI
• Gene ID: 6947
• mRNA Refseq: NM_001062
• Protein Refseq: NP_001053
• MIM: 189905
• Uniprot ID: P20061
• Chromosome Location: 11q11-q12
• Function: cobalamin binding