Recombinant Human TCN1 Protein (24-433 aa), His-tagged

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Recombinant Human TCN1 Protein (24-433 aa), His-tagged

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Cat.No. : TCN1-1533H
Product Overview : Recombinant Human TCN1 Protein (24-433 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Full Length of Mature Protein.
Description : Binds vitamin B12 with ftomolar affinity and protects it from the acidic environment of the stomach.
Source : Yeast
Species : Human
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 47.6 kDa
Protein length : 24-433 aa
AA Sequence : EICEVSEENY IRLKPLLNTM IQSNYNRGTS AVNVVLSLKL VGIQIQTLMQ KMIQQIKYNV KSRLSDVSSG ELALIILALG VCRNAEENLI YDYHLIDKLE NKFQAEIENM EAHNGTPLTN YYQLSLDVLA LCLFNGNYST AEVVNHFTPE NKNYYFGSQF SVDTGAMAVL ALTCVKKSLI NGQIKADEGS LKNISIYTKS LVEKILSEKK ENGLIGNTFS TGEAMQALFV SSDYYNENDW NCQQTLNTVL TEISQGAFSN PNAAAQVLPA LMGKTFLDIN KDSSCVSASG NFNISADEPI TVTPPDSQSY ISVNYSVRIN ETYFTNVTVL NGSVFLSVME KAQKMNDTIF GFTMEERSWG PYITCIQGLC ANNNDRTYWE LLSGGEPLSQ GAGSYVVRNG ENLEVRWSKY
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) [ Homo sapiens ]
Official Symbol : TCN1
Synonyms : TCN1; transcobalamin-1; haptocorin; haptocorrin; TC1; TCI; TC-1;
Gene ID : 6947
mRNA Refseq : NM_001062
Protein Refseq : NP_001053
MIM : 189905
UniProt ID : P20061

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