Recombinant Human TCN1 Protein (24-433 aa), His-tagged

• Cat.No.: TCN1-1533H
• Product Overview: Recombinant Human TCN1 Protein (24-433 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Full Length of Mature Protein.

Specification

• Description: Binds vitamin B12 with ftomolar affinity and protects it from the acidic environment of the stomach.
• Source: Yeast
• Species: Human
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 47.6 kDa
• Protein length: 24-433 aa
• AA Sequence: EICEVSEENYIRLKPLLNTMIQSNY NRGTSAVNVVLSLKLVGIQIQTLMQ KMIQQIKYNVKSRLSDVSSGELALI ILALGVCRNAEENLIYDYHLIDKLE NKFQAEIENMEAHNGTPLTNYYQLS LDVLALCLFNGNYSTAEVVNHFTPE NKNYYFGSQFSVDTGAMAVLALTCV KKSLINGQIKADEGSLKNISIYTKS LVEKILSEKKENGLIGNTFSTGEAM QALFVSSDYYNENDWNCQQTLNTVL TEISQGAFSNPNAAAQVLPALMGKT FLDINKDSSCVSASGNFNISADEPI TVTPPDSQSYISVNYSVRINETYFT NVTVLNGSVFLSVMEKAQKMNDTIF GFTMEERSWGPYITCIQGLCANNND RTYWELLSGGEPLSQGAGSYVVRNG ENLEVRWSKY
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) [ Homo sapiens ]
• Official Symbol: TCN1
• Synonyms: TCN1; transcobalamin-1; haptocorin; haptocorrin; TC1; TCI; TC-1
• Gene ID: 6947
• mRNA Refseq: NM_001062
• Protein Refseq: NP_001053
• MIM: 189905
• UniProt ID: P20061