"TGFB3" Related Products

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Recombinant Human Transforming Growth Factor, Beta 3

Cat. No.: TGFB3-376H
Product Overview: Recombinant human Xeno-free TGF beta 3 is expressed fromhuman 293 cellsas a mature disulfide-linked homodimer with apparent molecular mass of 25 kDa.
Description: Transforming growth factor beta-3 is a protein that in humans is encoded by the TGFB3 gene. It has been shown to interact with TGF beta receptor 2. This cytokine is produced in a human cell expression system with serum-free, chemically defined media. The cytokine is greater than 95% pure.
Source: Human 293 cells.
Activity: 0.1 to 0.5 ng/mL ED50.
Purity: >95%.
Endotoxin: Endotoxin-free.
Purity Confirmation: The protein was resolved by SDS polyacrylamide gel electrophoresis and the gel was stained with Coomassie blue.
Activity Assay: The specific activity was determined by the dose-dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2).
Pathways: Cell cycle; Chronic myeloid leukemia; Colorectal cancer; Cytokine-cytokine receptor interaction; Hypertrophic cardiomyopathy (HCM); MAPK signaling pathway; Pancreatic cancer;Pathways in cancer; Renal cell carcinoma; TGF-beta signaling pathway
Gene Name: TGFB3 transforming growth factor, beta 3 [ Homo sapiens ]
Synonyms: Transforming Growth Factor-beta3; TGFB3; ARVD; FLJ16571; TGF-beta3; transforming growth factor, beta 3
Gene ID: 7043
mRNA Refseq: NM_003239
Protein Refseq: NP_003230
MIM: 190230
UniProt ID: P10600
Chromosome Location: 14q24
Function: Growth factor activity; Identical protein binding; Protein heterodimerization activity; Transforming growth factor beta binding; Type I transforming growth factor beta receptor binding; Type II transforming growth factor beta receptor binding

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