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Official Full Name transforming growth factor, beta 3
Background This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and is involved in embryogenesis and cell differentiation. Defects in this gene are a cause of familial arrhythmogenic right ventricular dysplasia 1.
Synonyms TGFB3; transforming growth factor, beta 3; ARVD; FLJ16571; TGF-beta3; transforming growth factor beta-3; TGF-beta-3; MGC105479; MGC118722; TGF beta 3; TGF beta3; TGFB 3; TGFB3_HUMAN; transforming growth factor beta 3; OTTHUMP00000246179; OTTHUMP00000246180
    • Species :
    • Cattle
    • Chicken
    • Human
    • Mouse
    • Pig
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • CHO
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Insect Cell
    • Mammalian Cell
    • Nicotiana Benthamiana
    • Sf21 Insect Cell
    • Tag :
    • Avi
    • Fc
    • His
    • GST
    • T7
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TGFB3-105H Recombinant Human TGFB3 Protein E. coli
    Human TGFB3-006N Recombinant Human Transforming Growth Factor, Beta 3, Dimeric Form Nicotiana Benthamiana N/A
    Human TGFB3-007N Recombinant Human Transforming Growth Factor, Beta 3, Monomeric Form Nicotiana Benthamiana N/A
    Human TGFB3-017H Recombinant Human TGFB3 Protein E.coli N/A
    Human TGFB3-018H Recombinant Human TGFB3 Protein CHO N/A
    Human TGFB3-104HG GMP Recombinant Human TGFB3 Protein Insect Cell N/A
    Human TGFB3-1118HCL Recombinant Human TGFB3 293 Cell Lysate HEK293 N/A
    Human TGFB3-126H Recombinant Human TGFB3 Nicotiana Benthamiana N/A
    Human TGFB3-128H Recombinant Human TGFB3 Active Nicotiana Benthamiana N/A
    Human TGFB3-12H Recombinant Human TGFB3, His-tagged E.coli His
    Human TGFB3-1571H Recombinant human TGFB3, Active Nicotiana Benthamiana N/A
    Human TGFB3-193HG GMP Recombinant Human TGFB3 protein, Fc-tagged HEK293 Fc
    Human TGFB3-2462H Recombinant Human TGFB3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human TGFB3-31H Human Transforming Growth Factor-BETA 3 Reference standard N/A
    Human TGFB3-349H Recombinant Human Transforming Growth Factor, Beta 3 Sf21 Insect Cell N/A
    Human TGFB3-376H Recombinant Human Transforming Growth Factor, Beta 3 HEK293 N/A
    Human TGFB3-468H Recombinant Human Transforming Growth Factor, Beta 3, Dimeric Form Nicotiana Benthamiana N/A
    Human TGFB3-598H Recombinant Human Transforming Growth Factor, Beta 3 Human N/A
    Human TGFB3-600HB Recombinant Human TGFB3 protein, Avi-tagged, Biotinylated HEK293 Avi
    Human TGFB3-65H Recombinant Human Transforming Growth Ffactor, Beta 3 E.coli N/A
    Mouse Tgfb3-6390M Recombinant Mouse Tgfb3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat TGFB3-6038R Recombinant Rat Tgfb3 protein, His-tagged E.coli His
    Rhesus Macaque TGFB3-4688R Recombinant Rhesus monkey TGFB3 Protein, His-tagged Mammalian Cell His
    Chicken TGFB3-7004C Recombinant Chicken TGFB3 Mammalian Cell His
    Zebrafish TGFB3-9736Z Recombinant Zebrafish TGFB3 Mammalian Cell His
    Cattle TGFB3-2003C Recombinant Cattle TGFB3 protein, His & GST-tagged E.coli His/GST
    Pig TGFB3-2004P Recombinant Pig TGFB3 protein, His & T7-tagged E.coli His/T7

    tgfb3 involved in several pathways and played different roles in them. We selected most pathways tgfb3 participated on our site, such as MAPK signaling pathway, Cytokine-cytokine receptor interaction, FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with tgfb3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction KIT; GM-CSF; IL6ST; XCR1; TNFSF15; KITB; CXCR7; LEPA; IFNA4; PF4V1
    FoxO signaling pathway PRKAG2; PDPK1B; FOXO1A; PRKAG3; GABARAPL1; TGFB2; STAT3; INS; SGK2B; PDPK1
    Cell cycle RBBP4; SPO11; TCTN2; YWHAH; MCM7; SMC3; LIN9; TUBGCP3; TRP53; CHEK2
    Endocytosis VPS37A; SMAD2; GRK1B; CBL; EPN1; VPS36; RAB5AA; SH3GL1; VPS4B; SNX1A
    TGF-beta signaling pathway BMPR1B; ACVR1L; BMP8B; ACVR2A; SMURF1; ACVR1C; BMP7; INHBAB; BMPR1A; BMPR1AA
    Hippo signaling pathway PARD6A; WNT2B; PPP2R2D; CRB2; ACTB; FZD8; PARD3; BMP7; PPP1CC; BIRC2
    Chagas disease (American trypanosomiasis) CALR; SMAD2; AKT2; TICAM1; CCL3; TLR6; RELA; CFLAR; CCL3L1; MAP2K4
    Malaria CD40; CD40LG; IL12A; GYPB; ICAM1; CCL2; TGFB2; TGFB1; HBB-B1; TGFB3
    Toxoplasmosis MAPK9; MAPK10; HLA-DPB1; TAB2; LAMC2; LAMA2; MAPK8; HLA-DRB1; H2-AA; TRAF6
    Tuberculosis ITGB2L; IRAK2; MAPK11; STAT1; CD209A; RAB5B; MAPK3; TLR1; IFNA17; KSR1
    Hepatitis B FADD; TIRAP; NFATC4; MMP9; Ifna15; PTK2B; IFNA16; TP53; AKT2; IFNA13
    HTLV-I infection POLE; CDC27; PIK3R5; VDAC1; MAPK8; TNFRSF1A; CD3D; CD40; NFATC1; CCND1
    Pathways in cancer FZD5; SMAD4; RET; WNT6; ZBTB16; VEGFB; RXRA; AGTR1B; GNAQ; AXIN1
    Colorectal cancer TCF7L2; CCND1; PIK3CD; TGFB3; DCC; SMAD3; TP53; PIK3R3; Casp3; GSK3B
    Renal cell carcinoma TCEB2; CUL2; PIK3CA; TGFB2; TGFB3; SLC2A1; PIK3CG; PAK6; FH; PIK3CB
    Pancreatic cancer SMAD4; RALGDS; IKBKG; STAT1; BRCA2; RAC3; BRAF; MAPK8; CDC42; MAPK1
    Chronic myeloid leukemia IKBKG; MAP2K2; PIK3R5; MDM2; HDAC2; TGFBR2; KRAS; AKT1; STAT5B; RB1
    Inflammatory bowel disease (IBD) IL2RG; SMAD3; HLA-DMB; IL12RB1; IL18RAP; IL4R; RELA; HLA-DRB1; IL23; IFNG
    Rheumatoid arthritis IL11; ATP6V0E1; ICAM1; TGFB2; H2-AA; IL1B; ATP6V1E2; MMP3; TNFSF13; TLR4
    Hypertrophic cardiomyopathy (HCM) ITGA2; ITGA1; PRKAA1; DMD; TNNC1; ITGB6; TPM1; ITGA2B; SGCD; CACNG8
    Dilated cardiomyopathy CACNG2; MYH7; PLN; ITGA3; CACNA2D2; ITGA6; LAMA2; Adcy4; CACNG8; ITGA4

    tgfb3 has several biochemical functions, for example, cytokine activity, growth factor activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by tgfb3 itself. We selected most functions tgfb3 had, and list some proteins which have the same functions with tgfb3. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity Ccl12; BMP2B; FASLG; GPI1; IFNA13; FAM3C; MSTN; LEFTY2; HMGB1A; IL29
    growth factor activity BMP16; CTGF; HBEGF; FGF1B; NDP; NODAL; BTC; GPR19; FGF7; GDF6B
    identical protein binding FUS; GYPA; SEPHS1; KLHL7; TPRGL; VPS41; VWA2; FBXW7; TOPBP1; CBX3
    protein binding NUP133; KCNIP3; STYK1; YWHAQ; RAB9A; HNRPDL; AGTR1; SURF1; SBNO2; VASH1
    protein heterodimerization activity PHC2B; SMAD4; ADRa1A; BMP6; NKX2-5; HIST2H2AA4; UBA2; AXL; NFYBB; KCNK9
    transforming growth factor beta binding LTBP1; VASN; ENG; CD109; TGFBR1; TGFB3; THBS1; HYAL2; ACVR1; LTBP4
    type I transforming growth factor beta receptor binding TGFBR2; TGFB1; FKBP1A; ENG; SNX25; TGFB3; SMAD2; SMAD6; SMAD7
    type II transforming growth factor beta receptor binding TGFBR3; TGFB3; TGFB1; BAMBI; TGFB1A; ENG; TGFB2; TGFBR1
    type III transforming growth factor beta receptor binding TGFB1; TGFB2; TGFBR2; TGFB3

    tgfb3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with tgfb3 here. Most of them are supplied by our site. Hope this information will be useful for your research of tgfb3.


    Petra, H; Eva, H; et al. Molecular Profiling of Acute and Chronic Rejections of Renal Allografts. CLINICAL & DEVELOPMENTAL IMMUNOLOGY :-(2013).
    Le, M; Naridze, R; et al. Transforming Growth Factor Beta 3 Is Required for Excisional Wound Repair In Vivo. PLOS ONE 7:-(2012).

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