tgfb1 Protein, Transforming Growth Factor, Beta 1

tgfb1

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tgfb1

Official Full Name Transforming Growth Factor, Beta 1
Background Transforming growth factor beta 1 or TGF-β1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. In humans, TGF-β1 is encoded by the TGFB1 gene.
Synonyms Tgfb1; transforming growth factor, beta 1; CED; LAP; DPD1; TGFB; TGFbeta; TGF-beta 1 protein; latency-associated peptide; Camurati-Engelmann disease; Transforming growth factor beta-1; TGF-beta-1; Camui Engelmann disease; Diaphyseal dysplasia 1 progressive; TGF beta 1; TGF beta; TGF beta 1 protein; TGF-beta-5; TGF-beta1; Tgfb-1; TGFB1_HUMAN; TGFbeta1; Transforming Growth Factor b1; Transforming Growth Factor beta 1; Transforming growth factor beta 1a
    • Species :
    • Bovine
    • Canine
    • Cattle
    • Chicken
    • Cynomolgus
    • Cynomolgus Monkey
    • Dog
    • Guinea pig
    • Human
    • Mouse
    • Pig
    • Rabbit
    • Rat
    • Sheep
    • Source :
    • CHO
    • CHO cells
    • E.coli
    • HEK293
    • Human
    • Human Cell
    • Human cells
    • Human Platelet
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Avi
    • FC
    • GST
    • His
    • His & Avi
    • MBP
    • S
    • SUMO
    • T7
    • Human Fc
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TGFB1-014H Recombinant Human TGFB1 Protein CHO N/A
    Human TGFB1-02H Recombinant Human TGFB1 Protein, Fc-tagged Human cells FC
    Mouse TGFb1-33M Recombinant Mouse TGF-beta 1 Protein CHO cells N/A
    Human TGFB1-509H Recombinant Human TGFB1 protein, Fc-tagged HEK293 Human Fc
    Human TGF-137H Recombinant Human TGF protein HEK293 N/A
    Cynomolgus TGFB1-028C Recombinant Cynomolgus Tgfb1 Protein, His-tagged HEK293 His
    Mouse Tgfb1-045M Recombinant Mouse Tgfb1 Protein, His-tagged HEK293 His
    Human TGFB1-137H Recombinant Human TGFB1 protein, His & Avi-tagged HEK293 His & Avi
    Human TGFB1-137HB Recombinant Human TGFB1 protein, Avi-tagged, Biotinylated HEK293 Avi
    Human TGFB1-362H Recombinant Human TGFB1 protein, His-tagged, Biotinylated HEK293 His
    Human TGFB1-363H Recombinant Human TGFB1 Protein, His & Avi-tagged, Biotinylated HEK293 His/Avi
    Human TGFB1-364H Recombinant Human TGFB1 protein, Avi-tagged HEK293 Avi
    Bovine TGFB1-829B Recombinant Bovine TGFB1 Protein (279-390 aa), His-tagged E.coli His
    Human TGFB1-001HCL Recombinant Human TGFB1 cell lysate CHO N/A
    Human TGFB1-057H Recombinant Human TGFB1 Protein HEK293 N/A
    Human TGFB1-119H Recombinant Human Transforming Growth Factor, Beta 1, GST-tagged E.coli GST
    Human TGFB1-120H Recombinant Human TGFB1 CHO N/A
    Human TGFB1-126H Recombinant Human Transforming Growth Factor, beta 1 E.coli N/A
    Human TGFB1-134HG GMP Recombinant Human TGFB1 Protein CHO N/A
    Human TGFB1-159HG GMP Recombinant Human TGFB1 Protein HEK293 N/A
    Human TGFB1-196H Recombinant Human TGFB1 E.coli N/A
    Human TGFB1-219H Recombinant Human TGFB1, MIgG2a Fc-tagged CHO Fc
    Human TGFB1-21H Native Human TGF- β1 Human Platelet N/A
    Human TGFB1-244H Recombinant Human TGFB1 protein, His-tagged E.coli His
    Human TGFB1-2662HCL Recombinant Human TGFB1 cell lysate Human Cell N/A
    Human TGFB1-3209H Recombinant Human TGFB1, His-tagged E.coli His
    Human TGFB1-336H Recombinant Human TGFB1 protein, His-tagged HEK293 His
    Human TGFB1-345H Recombinant Human TGFB1 protein, His/MBP-tagged E.coli His/MBP
    Human TGFB1-428H Recombinant Human TGFB1 HEK293 N/A
    Human TGFB1-429H Recombinant Human TGFB1 Protein, His-tagged E.coli His
    Human TGFB1-4322H Recombinant Human TGFB1 protein, GST-tagged Wheat Germ GST
    Human TGFB1-489H Recombinant Human TGFB1, His tagged Human Cell His
    Human TGFB1-518H Recombinant Human TGFB1 protein HEK293
    Human TGFB1-539H Recombinant Human TGFB1 Human N/A
    Human TGFB1-594H Recombinant Human Transforming Growth Factor, Beta 1 Human N/A
    Human TGFB1-706H Recombinant Human TGFB1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human TGFB1-908H Recombinant Human Transforming Growth Factor, Beta 1, His-tagged E.coli His
    Human TGFB1-95H Human Transforming Growth Factor beta-1 (rDNA derived) Reference standard N/A
    Mouse TGFB1-001MCL Recombinant Mouse TGFB1 cell lysate Human Cell N/A
    Mouse Tgfb1-242M Recombinant Mouse Tgfb1 protein, His-tagged E.coli His
    Mouse Tgfb1-520M Recombinant Mouse Tgfb1, His-tagged Human Cell His
    Mouse TGFB1-576M Recombinant Mouse Tgfb1 HEK293 N/A
    Rat Tgfb1-1384R Recombinant Rat Tgfb1 Protein, His-SUMO-tagged E.coli His/SUMO
    Rat TGFB1-152R Recombinant Rat Tgfb1, His tagged Human Cell His
    Rat TGFB1-153R Recombinant Rat TGFB1 protein HEK293 N/A
    Rat Tgfb1-26R Recombinant Rat Tgfb1 Protein, His-tagged HEK293 His
    Rat Tgfb1-531R Recombinant Rat Tgfb1 protein, His-tagged E.coli His
    Rat TGFB1-6035R Recombinant Rat TGFB1 Protein Mammalian Cell His
    Rat TGFB1-803RCL Recombinant Rat TGFB1 cell lysate Human Cell N/A
    Cynomolgus Monkey TGFB1-1215C Recombinant Cynomolgus TGFB1 Protein, His-tagged HEK293 His
    Canine TGFB1-1051C Recombinant Canine TGFB1 Protein, His-tagged HEK293 His
    Dog TGFB1-525D Recombinant Dog TGFB1 protein, His & GST-tagged E.coli His/GST
    Bovine TGFB1-96B Bovine Transforming Growth Factor beta-1 Reference standard N/A
    Chicken TGFB1-526C Recombinant Chicken TGFB1 protein, His-tagged E.coli His
    Rabbit TGFB1-532R Recombinant Rabbit TGFB1 protein, His & T7-tagged E.coli His/T7
    Cattle TGFB1-524C Recombinant Cattle TGFB1 protein, His & GST-tagged E.coli His/GST
    Guinea pig Tgfb1-527G Recombinant Guinea pig Tgfb1 protein, His & S-tagged E.coli His/S
    Sheep TGFB1-529S Recombinant Sheep TGFB1 protein, His & GST-tagged E.coli His/GST
    Pig TGFB1-530P Recombinant Pig TGFB1 protein, His-tagged E.coli His

    tgfb1 involved in several pathways and played different roles in them. We selected most pathways tgfb1 participated on our site, such as MAPK signaling pathway, Cytokine-cytokine receptor interaction, FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with tgfb1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway IL1A; PTPN7; Fgf15; MAPK10; PRKACBB; CACNA2D4; CACNB4; PRKACB; MAP4K4; TGFBR2
    Cytokine-cytokine receptor interaction CCR8L; GDF5; CCR9; CSF2; OSTN; PDGFRA; Ccl9; IFNG1-2; NGFR; IL25
    FoxO signaling pathway INSB; IGF1RA; AKT2L; PTEN; PIK3R5; PRKAA1; RAF1A; CDKN1BB; PTENB; HOMER2
    Cell cycle TUBGCP5; MCM3L; CEP72; TUBGCP4; SSNA1; CTDNEP1A; AKAP9; PRKDC; SGOL2; ORC1
    Endocytosis CHMP5; ADRB2A; CXCR2; CDC42; ACAP2; PARD6A; VPS37C; GIT1; FMNL3; DNM2B
    TGF-beta signaling pathway AMH; MYCB; SMAD3; BMPR1B; INHBC; SMAD3A; SMAD4; ID1; SP1; TGFBR1A
    Osteoclast differentiation LILRB2; ACP5; CSF1; PPP3CB; FOSB; LILRA5; NFKB1; SIRPB1; CAMK4; NCF2
    Hippo signaling pathway BIRC5; BMPR2; WNT4; ACTG1; AJUBA; TCF7; WNT7A; BMPR1B; SOX2; BMP5
    Intestinal i ITGA4; CD86; MADCAM1; HLA-DRB1; TNFRSF13B; TNFSF13; TGFB1; CCL28; HLA-DRA; HLA-DRB5
    ne network for IgA production PIGR; HLA-DQB1; AICDA; IL15; HLA-DRB5; BLA; IL-15RA; HLA-DRB3; CXCL12B; CD28
    Non-alcoholic fatty liver disease (NAFLD) MAPK8; SDHD; AKT2; NDUFB7; UQCR10; TNFRSF1A; PIK3R5; PRKAG3; NDUFV3; RELA
    Leishmaniasis NCF1; TGFB2; HLA-DQA1; IL4; HLA-DRA; IRAK4; IL12A; HLA-DOB; TGFB3; NOS2
    Chagas disease (American trypanosomiasis) PIK3R2; PIK3CD; LOC100033925; BDKRB2; IL-8; MAPK3; FASLG; PPP2R2A; CXCL8; PLCB4
    Malaria MYD88; TGFB2; SDC1; KLRB1; SELE; ITGB2L; HBA2; CCL2; TLR9; HBB
    Toxoplasmosis LAMB1; BIRC2; BCL2; IRGM; IL12A; MAPK3; MAPK9; AKT1; PDPK1; PIK3CG
    Amoebiasis HSPB1; CTSG; COL1A1; SERPINB3; COL5A1; TNF; IL10; PIK3CA; LAMB1; IL1R1
    Tuberculosis HLA-DQB1; HLA-DOB; CLEC4E; SYK; CD74; EP300; CAMK2G; APAF1; PIK3C3; CAMK2B
    Hepatitis B CASP10; EGR2; TGFB3; PRKCA; IL6; Casp3; PCNA; STAT6; ELK1; IRF7
    HTLV-I infection RANBP1; WNT8B; POLD1; NFATC4; Adcy4; HLA-DMA; DLG1; ITGB2L; TP53INP1; PIK3CB
    Pathways in cancer KITLG; MMP9; PTCH1; F2RL3; ARHGEF1; GNAI1; VEGFB; FZD6; DAPK1; TFG
    Proteoglycans in cancer SOS1; ARHGEF1; ITGB1; WNT9B; FZD3; NRAS; SLC9A1; NANOG; STAT3; PIK3CB
    Colorectal cancer APC; MAP2K1; ARAF; APC2; RHOA; KRAS; MAPK1; TGFBR2; BIRC5; PIK3R1
    Renal cell carcinoma AHA-1; PTPN11; MAPK1; EP300; NRAS; PIK3R2; ARAF; CUL2; PIK3R3; HGF
    Pancreatic cancer RAC2; PIK3CD; CASP9; PIK3R2; MAP2K1; AKT1; TGFA; PIK3R3; ARAF; TP53
    Chronic myeloid leukemia RUNX1; IKBKB; TGFBR2; MAPK1; BCR; SHC1; CRK; BCL2L1; HRAS; MAPK3
    Inflammatory bowel disease (IBD) Il23a; Il12b; HLA-DRB5; TNF; IL18R1; HLA-DRB3; IL2RG; HLA-DRA; IL12A; Il4ra; HLA-DQA2
    Rheumatoid arthritis TNF; ATP6V1H; TGFB3; HLA-DRA; IL1A; FOS; ATP6V0D1; ATP6V1G1; IL18; ATP6V0C
    Hypertrophic cardiomyopathy (HCM) TPM4; SLC8A1; ITGA4; TTN; ACTB; TNNC1; ITGA6; ITGB6; IL6; TGFB2
    Dilated cardiomyopathy ITGA10; RYR2; CACNG2; TNF; ITGA2; PLN; CACNB2; ITGA5; TGFB1; ACTG1

    tgfb1 has several biochemical functions, for example, antigen binding, cytokine activity, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by tgfb1 itself. We selected most functions tgfb1 had, and list some proteins which have the same functions with tgfb1. You can find most of the proteins on our site.

    Function Related Protein
    antigen binding FCN2; Ighg2a; FCN3; LILRB4; MHC1UKA; IGHM; SPON2; IGLC2; IGKC; LILRA2
    cytokine activity OSM; GDF9; TXLNA; FASLG; C1QTNF4; IFNA2; IFNA21; LEFTY2; IL11; IFNG1-1
    enzyme binding HMGA1-RS1; Txn1; RPS2; RCOR3; HSPA1A; DVL1; PRKCA; ZNHIT6; CYP3A4; Alb
    glycoprotein binding B2M; BMPR1A; HSPA5; APOH; CD4; RAB14; RASA1; FYN; TGFB1; ITGB2
    growth factor activity BMP2B; INHBC; FGF8B; MDKA; IGF3; GDF9; PDGFC; NODAL; IL6; FGF8A
    protein N-terminus binding SMARCE1; RELA; PDLIM5; STX5A; EXOC4; PEX5; EIF5A; EIF3E; TBL1XR1; FEZ1
    protein binding GBA; EDA2R; TLX3; TOB1; C11orf65; PDIA2; EXOSC8; SGTB; LSM2; NOS2
    protein heterodimerization activity EXT1; VAPA; POLA1; SMAD2; HIST1H47; RAF1; SNX5; ITGB1A; GTF2A1; HIST4H4
    protein homodimerization activity HELT; MAP3K12; SRGAP2A; PSPH; STK4; HMOX1; DMRTB1; GSTA4; ID1; TFRC
    type I transforming growth factor beta receptor binding SMAD7; TGFB3; FKBP1A; SMAD6; TGFB1; ENG; TGFBR2; SMAD2; SNX25
    type II transforming growth factor beta receptor binding TGFB2; BAMBI; TGFB3; TGFBR3; TGFB1; TGFB1A; ENG; TGFBR1
    type III transforming growth factor beta receptor binding TGFB1; TGFB2; TGFB3; TGFBR2

    tgfb1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with tgfb1 here. Most of them are supplied by our site. Hope this information will be useful for your research of tgfb1.

    TGFBR2; APP; MEOX2; 80125; FSTL1; THBS1; ENG

    Mrizak, D; Martin, N; et al. Effect of Nasopharyngeal Carcinoma-Derived Exosomes on Human Regulatory T Cells. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE 107:-(2015).
    Wang, YD; Rajanbabu, V; et al. Transcriptome analysis of medaka following epinecidin-1 and TH1-5 treatment of NNV infection. FISH & SHELLFISH IMMUNOLOGY 42:121-131(2015).

    TGF

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