TGFB2

  • Official Full Name

    transforming growth factor, beta 2

  • Overview

    Transforming growth factor betas (TGF betas) mediate many cell-cell interactions that occur during embryonic development. Three TGFbs have been identified in mammals. TGF beta1, TGF beta2 and TGF beta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. This antibody reacts with the precursor and mature form of TGF beta2 and to a lesser extent TGF beta3, but does not cross react with TGF beta1.
  • Synonyms

    TGFB2; transforming growth factor, beta 2; transforming growth factor beta-2; G-TSF; cetermin; polyergin; BSC-1 cell growth inhibitor; glioblastoma-derived T-cell suppressor factor; TGF-beta2; MGC116892; LDS4;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • GMP Proteins
  • Transfected Stable Cell Lines
  • Bovine
  • Canine
  • Cattle
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus
  • Rhesus Macaque
  • Zebrafish
  • CHO
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Hi-5 Insect Cell
  • Human
  • Human Cell
  • Human cells
  • Mammalian Cell
  • Mammalian cells
  • Nicotiana Benthamiana
  • C
  • His
  • Fc
  • Flag
  • His (Fc)
  • Avi
  • His(C
  • ter)
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TGFB2-22H Active Recombinant Human TGFB2, His-tagged Nicotiana Benthamiana His
Human TGFB2-519H Active Recombinant human TGFB2 HEK293 N/A
Human TGFB2-540H Active Recombinant Human TGFB2 Human His
Human TGFB2-8328H Active Recombinant Human TGFB2 Hi-5 Insect Cell N/A
Human TGFB2-632H Active Recombinant Human Transforming Growth Factor, Beta 2 Human N/A
Human TGFB2-015H Active Recombinant Human TGFB2 Protein CHO N/A
Human TGFB2-016H Active Recombinant Human TGFB2 Protein HEK293 N/A
Human TGFB2-127H Active Recombinant Human TGFB2, Animal Free Nicotiana Benthamiana N/A
Human TGFB2-577H Active Recombinant Human Transforming Growth Factor, Beta 2 E.coli N/A
Human TGFB2-377H Active Recombinant Human Transforming Growth Factor, Beta 2 HEK293 N/A
Human TGFB2-2196H Active Recombinant Human TGFB2 protein, His-tagged HEK293 His
Human TGFB2-31244TH Recombinant Human TGFB2 N/A
Human TGFB2-556H Recombinant Human TGFB2, His tagged Human Cell His
Human TGFB2-438H Recombinant Human Transforming Growth Factor Beta 2 E.coli N/A
Human TGFB2-1566H Recombinant human TGFB2, Active Nicotiana Benthamiana N/A
Human TGFB2-633H Recombinant Human Transforming Growth Factor, Beta 2, His-tagged Human His
Human TGFB2-228H Recombinant Human TGFB2 Protein, His-tagged E.coli His
Human TGFB2-467H Recombinant Human Transforming Growth Factor, Beta 2, Monomeric Form Nicotiana Benthamiana N/A
Human TGFB2-348H Recombinant Human Transforming Growth Factor, Beta 2 Mammalian cells N/A
Human TGFB2-004N Recombinant Human Transforming Growth Factor, Beta 2, Dimeric Form Nicotiana Benthamiana N/A
Human TGFB2-1119HCL Recombinant Human TGFB2 293 Cell Lysate HEK293 N/A
Human TGFB2-104H Active Recombinant Human TGFB2 Protein E. coli
Human TGFB2-47H Active Recombinant Human TGFB2 Protein, Animal Free Human cells
Human TGFB2-2181H-B Recombinant Human TGFB2 Protein Pre-coupled Magnetic Beads HEK293
Human TGFB2-2181H Recombinant Human TGFB2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human TGFB2-1561HG Active GMP Recombinant Human TGFB2 protein, Fc-tagged HEK293 Fc
Human TGFB2-287H Active Recombinant Human TGFB2 Protein (Ala303-Ser414), C-His tagged, Animal-free, Carrier-free E.coli C-His
Human TGFB2-2893H Recombinant Human TGFB2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human TGFB2-302H Recombinant Active Human TGFB2 Protein, His-tagged(C-ter) E.coli His(C-ter)
Human TGFB2-1502HFL Recombinant Full Length Human TGFB2 Protein, C-Flag-tagged Mammalian cells Flag
Mouse Tgfb2-620M Active Recombinant Mouse Tgfb2 CHO N/A
Mouse TGFB2-16704M Recombinant Mouse TGFB2 protein, His-tagged HEK293 His
Mouse Tgfb2-849M Recombinant Mouse Tgfb2 protein, His-tagged, Biotinylated HEK293 His
Mouse Tgfb2-6389M Recombinant Mouse Tgfb2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse TGFB2-9161M Recombinant Mouse TGFB2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Tgfb2-849MB Recombinant Mouse Tgfb2 protein, His-tagged, Biotinylated HEK293 His
Mouse TGFB2-9161M-B Recombinant Mouse TGFB2 Protein Pre-coupled Magnetic Beads HEK293
Mouse TGFB2-127M Recombinant Mouse TGFB2 Protein Human Cell
Rat Tgfb2-229R Recombinant Rat Tgfb2 Protein, His-tagged E.coli His
Rat TGFB2-6037R Recombinant Rat TGFB2 Protein Mammalian Cell His
Rat TGFB2-5695R-B Recombinant Rat TGFB2 Protein Pre-coupled Magnetic Beads HEK293
Rat TGFB2-5695R Recombinant Rat TGFB2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bovine TGFB2-97B Bovine Transforming Growth Factor beta-2 Reference standard N/A
Canine TGFB2-1053C Recombinant Canine TGFB2 protein, His-tagged HEK293 His
Cattle TGFB2-227C Recombinant Cattle TRIM21 Protein, His-tagged E.coli His
Rhesus TGFB2-1119R Recombinant Rhesus TGFB2 protein(Met1-Ser414), His-tagged HEK293 C-His
Rhesus Macaque TGFB2-4687R Recombinant Rhesus monkey TGFB2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque TGFB2-4501R-B Recombinant Rhesus Macaque TGFB2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque TGFB2-4501R Recombinant Rhesus Macaque TGFB2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish TGFB2-9735Z Recombinant Zebrafish TGFB2 Mammalian Cell His
Chicken TGFB2-2725C Recombinant Chicken TGFB2 Mammalian Cell His
Chicken TGFB2-1252C Recombinant Chicken TGFB2 Protein, His-tagged E.coli N-His
Chicken TGFB2-1253C Recombinant Chicken TGFB2 Protein, His-tagged E.coli N-His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TGFB2 Related Articles
  • TGFB2 Related Gene Family
  • TGFB2 Related Research Area
  • TGFB2 Related Signal Pathway

TGFB2 involved in several pathways and played different roles in them. We selected most pathways TGFB2 participated on our site, such as MAPK signaling pathway, Cytokine-cytokine receptor interaction, FoxO signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with TGFB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwayARR3B;MAP2K3;AKT2L;STMN1;MAPK8A;PPM1B;MAPT;PRKCBB;ATF4
Cytokine-cytokine receptor interactionTNFRSF9A;CXCL10;CSF1R;IFNPHI3;IL26;TNFRSF1A;IL22RA1;FLT4;CXCL5
FoxO signaling pathwayPRKAB1A;CCND1;PRKAA2;STK4;PIK3CA;PLK2B;HRAS;KLF2B;CDKN1BB
Cell cycleCCNE1;FOXM1;MYBL2;MAU2;GINS1;CCNA2;VRK2;NUMA1;DPF1
EndocytosisDNM1A;SH3GLB2A;PIP5KL1;RNF103-CHMP3;FGFR2;STRUMPELLIN;ASAP2;STAMBPB;CHMP6B
TGF-beta signaling pathwayZFYVE16;TGIF1;ID2B;GDF5;SMAD3A;RBL1;SMAD7B;SMAD6;TGFB2
Osteoclast differentiationLILRB1;FCGR2B;NFATC1;STAT1;MAPK8;PPP3R2;SIRP-BETA;AKT1;IKBKG
Hippo signaling pathwayTEAD3;APC2;WNT8B;BMP7;FZD1;YWHAE;CRB1;LLGL1;DLG1
LeishmaniasisNFKBIB;IL12A;HLA-DPB1;RELA;TAB2;HLA-DRB1;TGFB3;TGFB2;HLA-DRB4
Chagas disease (American trypanosomiasis)PPP2CA;IL12A;IFNG;CD3E; CD3D;NOS2;FOS;FAS;PPP2R1A;C1QB
MalariaCSF3;IL-8;HBB-B2;ITGB2L;KLRK1;COMP;HBA2;IL6;SDC2
ToxoplasmosisPIK3R1;PPIF;HLA-DQA1;IL10RB;BIRC7;PDPK1;MAPK12;LAMC1;IFNGR1
AmoebiasisSERPINB4;GM-CSF;GNAQ;SERPINB6B;C8A;PLCB3;PIK3CB;PRKACA;GNAS
TuberculosisAKT1;MAPK11;Itgam&Itgb2;MYD88;ITGAM;FCGR1A;CAMK2B;PPP3CC;PLK3
Hepatitis BMAPK10;MAPK3;IFNA1;TBK1;IRF3;TLR3;CXCL8;ATP6AP1;MAPK9
HTLV-I infectionCD3E;GSK3B;NFATC1;VCAM1;KAT2B;ITGB2;HLA-DQA2;ANAPC2;H2-Q10
Pathways in cancerMET;PIK3R5;SMAD3;Ar;EGLN2;MAP2K2;PIK3CG;IGF1;GNAI2
Proteoglycans in cancerCAV3;ERBB2;FLNC;GPC1;PIK3R2;PDCD4;HPSE;AKT1;PLCG1
MicroRNAs in cancerMAPK1;NOTCH1;WNT3;PIM1;TPM1;DDIT4;RASSF1;PDGFB;CD44
Colorectal cancerFOS;MSH3;TGFB3;RAC3;ARAF;TCF7L2;BRAF;RALGDS;MAPK8
Renal cell carcinomaAKT2;TCEB1;MAP2K2;RAP1A;EGLN2;PAK2;PDGFB;PIK3R2;GAB1
Pancreatic cancerPLD1;VEGFA;PIK3R5;AKT1;IKBKB;CCND1;CDC42;SMAD4;BRAF
Chronic myeloid leukemiaPIK3CB;PIK3R3;SHC2;NRAS;TP53;PIK3R2;BAD;SOS1;PIK3R1
Inflammatory bowel disease (IBD)SMAD2;IL17A;Il4ra;HLA-DMA;IL1B;STAT3;H2-AB1;IL6;IL18R1
Rheumatoid arthritisATP6V0A4;CXCL12;ATP6V0C;CCL3L1;CD28;HLA-DQB1;ATP6V0E1;HLA-DRB4;ATP6V1H
Hypertrophic cardiomyopathy (HCM)CACNG4;MYL3;ITGA9;ITGA2B;RYR2;DAG1;ITGA6;ACTG1;TGFB3
Dilated cardiomyopathyCACNG6;CACNG3;TNF;CACNA2D2;ACTB;EMD;ITGA2;TGFB2;TGFB1

TGFB2 has several biochemical functions, for example, beta-amyloid binding, cytokine activity, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TGFB2 itself. We selected most functions TGFB2 had, and list some proteins which have the same functions with TGFB2. You can find most of the proteins on our site.

Function Related Protein
beta-amyloid bindingTM2D1;APBB1;BCHE;HSD17B10;OLFM1;ACHE;Apba1;TGFB2;APBB2
cytokine activityIL6;LTA;Ifnz;CCL20A.3;IL17A/F1;Il1f9;IFNA2;IFNK;IL33
growth factor activityBMP3;Artn;IGF2;IGF2B;FGF20B;NTF3;NTF7;FGF4;LIF
protein bindingLMO2;OS9;IL1A;PRRC1;POGZ;BCL2L11;COPS4;SCRN1;MED12
protein heterodimerization activityXBP1;MAPK6;H2AFX;USF2;MCL1B;KCNH1;LIMK2;IL12A;ADRa1A
protein homodimerization activitySYNDIG1;TBX18;UBE4A;HMGCL;CD200;SFTPC;CEP57;BST2;SIAH1A
receptor bindingWNT7AA;NUDT19;MSN;FGG;FGF20B;CD160;LHB;LRRC4B;GSTM7
receptor signaling protein serine/threonine kinase activityTGFBR1;STK39;ALPK2;PAK2B;STK26;ACVR2B;ACVR1B;OXSR1B;ACVR1C
transforming growth factor beta receptor bindingINHBAA;GDF5;INHA;MSTNB;GDF6B;LFT1;MSTNA;GDF11;FKBP1A
type II transforming growth factor beta receptor bindingTGFB1A;ENG;TGFB1;TGFBR3;TGFB2;TGFB3;BAMBI;TGFBR1
type III transforming growth factor beta receptor bindingTGFB3;TGFBR2;TGFB1;TGFB2

TGFB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TGFB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TGFB2.

APP; BMP2

Niarami, MD; Masoudi, AA; et al. ASSOCIATION OF SINGLE NUCLEOTIDE POLYMORPHISM OF GHSR AND TGFB2 GENES WITH GROWTH AND BODY COMPOSITION TRAITS IN SIRE AND DAM LINES OF A BROILER CHICKEN. ANIMAL BIOTECHNOLOGY 25:13-22(2014).
Liu, NM; Yokota, T; et al. Transcription Profiles of Endothelial Cells in the Rat Ductus Arteriosus during a Perinatal Period. PLOS ONE 8:-(2013).
TGF
  • Q&As
  • Reviews

Q&As (6)

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What is the role of TGFB2 in wound healing and tissue repair? 05/16/2022

It can promote wound healing and tissue repair by stimulating the proliferation and migration of fibroblasts and epithelial cells, as well as promoting collagen synthesis.

Are there potential applications for TGFB2 inhibitors or activators? 02/12/2022

Inhibitors or activators targeting TGFB2 may have potential applications for the treatment of a variety of diseases, including cancer, inflammatory diseases, autoimmune diseases, etc.

How does TGFB2 regulate cell proliferation and differentiation? 10/15/2021

TGFB2 can regulate cell proliferation and differentiation by binding to its receptor and activating downstream signal transduction pathways.

What is the relationship between TGFB2 and immune regulation? 03/28/2021

This protein can be used as an immunomodulator to participate in the differentiation and function of immune cells, as well as the regulation of inflammatory responses.

How is the expression level of TGFB2 regulated? 11/03/2020

The expression level of TGFB2 is regulated by a variety of factors, including transcription factors, signal transduction pathways, and epigenetic modifications.

What is the association of TGFB2 with other proteins or cytokines? 09/17/2020

TGFB2 has a variety of associations with other proteins and cytokines. For example, it may interact with vascular endothelial growth factor (VEGF) and be involved in angiogenesis, and may also interact with apoptosis-related proteins to regulate the apoptotic process.

Customer Reviews (3)

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Reviews
11/19/2022

    No complicated experimental steps, suitable for beginners.

    06/28/2022

      Excellent performance in Western blot, even if stored for a long time will not affect its performance.

      07/18/2021

        The endotoxin levels were low enough not to interfere with the results.

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