GLP1R Activated GPCR Internalization Assay Kit
Cat.No. : | Kit-1263 |
Product Overview : | Activated GPCR Internalization cells are engineered to co-an untagged GPCR, Enzyme Acceptor (EA) tagged β-Arrestin, and a ProLink (PK) tag localized to the endosomes. Activation of the GPCR induces β-Arrestin recruitment, followed by internalization of the Receptor/Arrestin-EA complex in PK-tagged endosomes. This forces complementation of the two β-galactosidase enzyme fragments (EA and PK), forming functional enzyme that hydrolyzes substrate to generate a chemiluminescent signal. These cells have been modified to prevent long term propagation and expansion using a proprietary compound that has no apparent effect on assay performance. |
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Size : | 100 dp(1 x 96-well)/200 dp(2 x 96-well)/1000 dp(10 x 96-well) |
Storage : | Short term (2 weeks): Store in vapor phase of liquid N2 |
Products Types
◆ Recombinant Protein | ||
GLP1R-01D | Recombinant Dog GLP1R Protein, His-tagged | +Inquiry |
Glp1r-04M | Recombinant Mouse Glp1r Protein, His-tagged | +Inquiry |
GLP1R-1228H | Recombinant Human GLP1R Protein, His-tagged | +Inquiry |
GLP1R-294C | Recombinant Cynomolgus Monkey GLP1R Protein, His (Fc)-Avi-tagged | +Inquiry |
GLP1R-22H | Recombinant Human GLP1R Protein, Biotinylated | +Inquiry |
◆ Assay kits | ||
Kit-1259 | cAMP GLP1R CHO-K1 GPCR Assay Kit | +Inquiry |
Kit-1264 | GLP1R CHO-K1 β-Arrestin GPCR Assay Kit | +Inquiry |
Kit-1262 | cAMP CHO-K1 GLP1R Bioassay Kit | +Inquiry |
Kit-1268 | CHO-K1 GLP1R Bioassay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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