Active Native Human Lactate Dehydrogenase 2

• Cat.No.: LDH2-123H
• Product Overview: Native Human Lactate Dehydrogenase 2 was purified from Human Heart.

Specification

• Description: This gene encodes an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on the X chromosome and on chromosome. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Source: Human Heart
• Species: Human
• Form: Ammonium Sulfate Suspension
• Bio-activity: >/=50 U/mg protein
• Unit Definition: One unit will catalyze the transformation of one micromole of L-lactate to pyruvate per minute at 37C and pH 8.55.
• Concentration: >1.0 mg/mL

Gene Information

• Gene Name: LDHB lactate dehydrogenase B [ Homo sapiens ]
• Official Symbol: LDHB
• Synonyms: LDHB; lactate dehydrogenase B; L-lactate dehydrogenase B chain; LDH heart subunit; lactate dehydrogenase H chain; renal carcinoma antigen NY-REN-46; LDH-B; LDH-H; LDHBD; TRG-5
• Gene ID: 3945
• mRNA Refseq: NM_001174097
• Protein Refseq: NP_001167568
• MIM: 150100
• UniProt ID: P07195
• Chromosome Location: 12p12.2-p12.1
• Pathway: Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Glycolysis / Gluconeogenesis, organism-specific biosystem; Glycolysis / Gluconeogenesis, conserved biosystem; Glycolysis and Gluconeogenesis, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem
• Function: L-lactate dehydrogenase activity; NAD binding; identical protein binding; oxidoreductase activity