|Official Full Name||lactate dehydrogenase B|
|Background||This gene encodes an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on the X chromosome and on chromosome. Multiple alternatively spliced variants, encoding the same protein, have been identified.|
|Synonyms||LDHB; lactate dehydrogenase B; L-lactate dehydrogenase B chain; LDH heart subunit; lactate dehydrogenase H chain; renal carcinoma antigen NY-REN-46; LDH-B; LDH-H; LDHBD; TRG-5|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
LDHB involved in several pathways and played different roles in them. We selected most pathways LDHB participated on our site, such as Glycolysis / Gluconeogenesis, Cysteine and methionine metabolism, Pyruvate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with LDHB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Glycolysis / Gluconeogenesis||ENO1B; HKDC1; LDHC; ALDH3B2; ALDOAB; G6PC3; FBP1A; PFKMA; ALDH2.1; PKMA|
|Cysteine and methionine metabolism||AMD1; DNMT3AB; DNMT3A; LDHBA; GCLM; APIP; MTR; DNMT3B; SDS; MDH2|
|Pyruvate metabolism||PDHA1; ACACB; MDH2; GRHPRA; ME3; FH1; LDHB; PCK2; ALDH7A1; PDP1|
|Propanoate metabolism||ACSS2; PCCB; BCKDHA; MLYCD; ACACB; HADHAA; HADHA; HADHAB; MCEE; DLDH|
|Metabolic pathways||GCLC; NMNAT2; NMRK2; PIGK; NME5; CYP51A1; REV3L; ST6GAL2; GALNT4; INPP5B|
LDHB has several biochemical functions, for example, L-lactate dehydrogenase activity, NAD binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LDHB itself. We selected most functions LDHB had, and list some proteins which have the same functions with LDHB. You can find most of the proteins on our site.
|L-lactate dehydrogenase activity||LDHA; LDHBB; LDHBA; LDHAL6A; LDHAL6B; LDHC; LDHB|
|NAD binding||PARP1; IDH3A; HIBADHA; IDH2; GRHPRA; GLYR1; AOX3L1; IDH3G; GAPDHS; GPD1|
|identical protein binding||CRYAA; SIAH1; PON2; HSP90AA1; VWA1; CIDEB; ZNF212; ERN1; S100B; GNPNAT1|
|kinase binding||RPS3; SP100; PFKM; CTNNB1; CHP1; JAKMIP2; TENC1; PTPN22; ABI2; EMP2|
|protein binding||PTMA; MRPL1; EP300; GPATCH8; LMO1; COMMD10; TAF6L; TBRG1; NPHP4; ANO6|
LDHB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LDHB here. Most of them are supplied by our site. Hope this information will be useful for your research of LDHB.
LDHA; PEX5; VCAM1; LRRK2; TERF1; RAC3; YWHAZ; TBK1; LDHA; artM4