Recombinant Full Length Human MEF2D Protein, C-Flag-tagged

• Cat.No.: MEF2D-598HFL
• Product Overview: Recombinant Full Length Human MEF2D Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 55.8 kDa
• AA Sequence: MGRKKIQIQRITDERNRQVTFTKRK FGLMKKAYELSVLCDCEIALIIFNH SNKLFQYASTDMDKVLLKYT EYNEPHESRTNADIIETLRKKGFNG CDSPEPDGEDSLEQSPLLEDKYRRA SEELDGLFRRYGSTVPAPNF AMPVTVPVSNQSSLQFSNPSGSLVT PSLVTSSLTDPRLLSPQQPALQRNS VSPGLPQRPASAGAMLGGDL NSANGACPSPVGNGYVSARASPGLL PVANGNSLNKVIPAKSPPPPTHSTQ LGAPSRKPDLRVITSQAGKG LMHHLTEDHLDLNNAQRLGVSQSTH SLTTPVVSVATPSLLSQGLPFSSMP TAYNTDYQLTSAELSSLPAF SSPGGLSLGNVTAWQQPQQPQQPQQ PQPPQQQPPQPQQPQPQQPQQPQQP PQQQSHLVPVSLSNLIPGSP LPHVGAALTVTTHPHISIKSEPVSP SRERSPAPPPPAVFPAARPEPGDGL SSPAGGSYETGDRDDGRGDF
  GPTLGLLRPAPEPEAEGSAVKRMRL DTWTLKTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transcription Factors

Gene Information

• Gene Name: MEF2D myocyte enhancer factor 2D [ Homo sapiens (human) ]
• Official Symbol: MEF2D
• Synonyms: DKFZp686I1536
• Gene ID: 4209
• mRNA Refseq: NM_005920.4
• Protein Refseq: NP_005911.1
• MIM: 600663
• UniProt ID: Q14814