MEF2B
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Official Full Name
myocyte enhancer factor 2B -
Synonyms
MEF2B;myocyte enhancer factor 2B;myocyte-specific enhancer factor 2B;RSRFR2;serum response factor-like protein 2;MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B);FLJ32648
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MEF2B-8329Z | Recombinant Zebrafish MEF2B | Mammalian Cells | Zebrafish | His |
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| MEF2B-1075HCL | Recombinant Human MEF2B cell lysate | Human | Non |
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| Mef2b-4025M | Recombinant Mouse Mef2b Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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| MEF2B-4458H | Recombinant Human MEF2B Protein, GST-tagged | Wheat Germ | Human | GST |
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Involved Pathway
MEF2B involved in several pathways and played different roles in them. We selected most pathways MEF2B participated on our site, such as Adipogenesis,CDO in myogenesis,Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with MEF2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Developmental Biology | PLXND1,AP2M1,EFNA2,SPTB,RHOGA,FOXH1,LGI2B,ARPC5,BOC,SPTBN1 |
| SRF and miRs in Smooth Muscle Differentiation and Proliferation | NKX2 |
| miRs in Muscle Cell Differentiation | ELSPBP1 |
| Energy Metabolism | PPARGC1B,UCP2,ESRRA,TFB2M,MYBBP1A,GABPA,UCP3,TFB1M |
| cGMP-PKG signaling pathway | BDKRB2,INS,CALM4,SLC25A6,NFATC1,PPP1CC,PIK3CD,CALM1,PPP1R12A,ITPR1 |
| Adipogenesis | NR2F1,EGR2B,CELF1,CTNNB1,BMP1,RETN,EBF1,CEBPD,DVL1,CEBPA |
| Myogenesis | SPAG9,MYF6,TCF3A,CDH4,MYOD1,BNIP2,TCF4,TCF3B,BOC,MYOG |
| CDO in myogenesis | TCF3A,MYF6,CDH2,MYOG,MYOD1,TCF4,TCF12,CTNNA1,CDON,TCF3B |
Protein Function
MEF2B has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,histone deacetylase binding,protein dimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MEF2B itself. We selected most functions MEF2B had, and list some proteins which have the same functions with MEF2B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | HES6,ATF4B2,ZNF134,PPARAB,MYOG,KLF17,MSRB2,GCM1,TBX5B,PA2G4B |
| protein dimerization activity | ASCL1A,HIF1AL2,MXD1,PEX3,ASCL5,PIP,HER12,HNF1A,BETA3,HER8.2 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | RBPJB,YBX1,GMEB2,ASCL1,NR5A2,KLF16,CTCF,CDX4,CEBPG,KCNA3 |
| histone deacetylase binding | SP2,MEF2D,NCOR2,SP1,SKOR2,NKX2-5,CCND1,MAGEA1,GLI3,HDAC9 |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | HOXA5,PAX8,NRF1,PAX5,FOXI1,STK16,FOXJ1,MEIS1,GMEB1,NKX2-8 |
Interacting Protein
MEF2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MEF2B here. Most of them are supplied by our site. Hope this information will be useful for your research of MEF2B.
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