Recombinant Human HLA-G&B2M Protien, His-Avi-tagged, Biotinylated
Cat.No. : | HLA-G&B2M-392HB |
Product Overview : | Recombinant Biotinylated Human HLA-G Complex Tetramer Protein(P61769&P17693) is expressed from Expi293 with His and Avi Tag at the C-terminal. It contains Gly25-Thr305 (HLA-G),Ile21-Met119 (B2M) and RIIPRHLQL peptide. |
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Description : | HLA-G is a molecule that was first known to confer protection to the fetus from destruction by the immune system of its mother, thus critically contributing to fetal-maternal tolerance. The first functional finding constituted the basis for HLA-G research and can be summarized as such: HLA-G, membrane-bound or soluble, strongly binds its inhibitory receptors on immune cells (NK, T, B, monocytes/dendritic cells), inhibits the functions of these effectors, and so induces immune inhibition. |
Source : | HEK293 |
Species : | Human |
Tag : | His-Avi |
Form : | Supplied as 0.22um filtered solution in PBS (pH 7.4). |
Molecular Mass : | The protein has a predicted MW of 258 kDa.Due to glycosylation, the protein migrates to 230-260 KDa based on Bis-Tris PAGE result. |
Protein length : | It contains Gly25-Thr305 (HLA-G),Ile21-Met119 (B2M) and RIIPRHLQL peptide. |
Endotoxin : | Less than 1EU per ug by the LAL method. |
Purity : | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | HLA-G major histocompatibility complex, class I, G [ Homo sapiens ] |
Official Symbol : | HLA-G; B2M |
Synonyms : | LA class I histocompatibility antigen; alpha chain G; HLA G antigen; MHC class I antigen G; sHLA-G; HLA-G; B2M |
Gene ID : | 3135 |
mRNA Refseq : | NM_002127 |
Protein Refseq : | NP_002118 |
MIM : | 142871 |
UniProt ID : | P17693 |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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