Recombinant Human MPO Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: MPO-4004H
• Product Overview: MPO MS Standard C13 and N15-labeled recombinant protein (NP_000241) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 83.7 kDa
• AA Sequence: MGVPFFSSLRCMVDLGPCWAGGLTA EMKLLLALAGLLAILATPQPSEGAA PAVLGEVDTSLVLSSMEEAKQLVDK AYKERRESIKQRLRSGSASPMELLS YFKQPVAATRTAVRAADYLHVALDL LERKLRSLWRRPFNVTDVLTPAQLN VLSKSSGCAYQDVGVTCPEQDKYRT ITGMCNNRRSPTLGASNRAFVRWLP AEYEDGFSLPYGWTPGVKRNGFPVA LARAVSNEIVRFPTDQLTPDQERSL MFMQWGQLLDHDLDFTPEPAARASF VTGVNCETSCVQQPPCFPLKIPPND PRIKNQADCIPFFRSCPACPGSNIT IRNQINALTSFVDASMVYGSEEPLA RNLRNMSNQLGLLAVNQRFQDNGRA LLPFDNLHDDPCLLTNRSARIPCFL AGDTRSSEMPELTSMHTLLLREHNR LATELKSLNPRWDGERLYQEARKIV GAMVQIITYRDYLPLVLGPTAMRKY LPTYRSYNDSVDPRIANVFTNAFRY GHTLIQPFMFRLDNRYQPMEPNPRV PLSRVFFASWRVVLEGGIDPILRGL MATPAKLNRQNQIAVDEIRERLFEQ VMRIGLDLPALNMQRSRDHGLPGYN AWRRFCGLPQPETVGQLGTVLRNLK LARKLMEQYGTPNNIDIWMGGVSEP LKRKGRVGPLLACIIGTQFRKLRDG DRFWWENEGVFSMQQRQALAQISLP RIICDNTGITTVSKNNIFMSNSYPR DFVNCSTLPALNLASWREASTRTRP LEQKLISEEDLAANDILDYKDDDDK V
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MPO myeloperoxidase [ Homo sapiens (human) ]
• Official Symbol: MPO
• Synonyms: MPO; myeloperoxidase; myeloperoxidase; EC 1.11.2.2
• Gene ID: 4353
• mRNA Refseq: NM_000250
• Protein Refseq: NP_000241
• MIM: 606989
• UniProt ID: P05164