MPO

  • Official Full Name

    myeloperoxidase

  • Overview

    Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq, Jul 2008]
  • Synonyms

    MPO; myeloperoxidase;

  • Native Proteins
  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Cattle
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293 cells
  • HEK293T
  • Human Cells
  • Human Neutrophil
  • Human Sputum
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Neutrophils
  • Wheat Germ
  • C
  • His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MPO -27H Active Native Human Myeloperoxidase Human Sputum N/A
Human MPO-01H Active Native Human MPO Protein Neutrophils
Human MPO-63H Recombinant Human Myeloperoxidase E.coli N/A
Human MPO-54H Recombinant Human Myeloperoxidase E.coli His
Human MPO-49H Recombinant Human MPO protein, His-tagged E.coli His
Human MPO-2636H Recombinant Human MPO protein, His-tagged E.coli His Val165~Gly278
Human MPO-493H Recombinant Human MPO protein, His-tagged HEK293 His 165-278aa
Human MPO-29360TH Recombinant Human MPO, GST-tagged E.coli GST
Human MPO-4234HCL Recombinant Human MPO 293 Cell Lysate HEK293 N/A
Human MPO-4004H Recombinant Human MPO Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MPO-5506H Recombinant Human MPO Protein, GST-tagged Wheat Germ GST
Human MPO-1300HFL Recombinant Full Length Human MPO Protein, C-Flag-tagged Mammalian cells Flag
Human MPO-8220H Native Human Neutrophil Myeloperoxidase Human Neutrophil N/A
Human MPO-1427H-B Recombinant Human MPO Protein Pre-coupled Magnetic Beads HEK293
Human MPO-2943H Recombinant Human MPO Protein, GST-tagged E.coli GST
Human MPO-4593H Recombinant Human MPO Protein (Met1-Ser745), C-His tagged Mammalian cells C-His Met1-Ser745
Human MPO-1427H Recombinant Human MPO Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human MPO-0279H Recombinant Human MPO protein, His-tagged HEK293 His Met1-Ser745
Human MPO-527H Recombinant Human MPO Protein (Met1-Ser745), His-tagged Insect Cell His Met1-Ser745
Human MPO-4594H Recombinant Human MPO Protein (Cys606-Ser745), N-His tagged E.coli N-His Cys606-Ser745
Human MPO-51H Recombinant Human MPO Protein, His-tagged Human Cells His
Human MPO-0030H Recombinant Human MPO Protein HEK293 cells
Mouse Mpo-418M Active Recombinant Mouse Mpo, His-tagged Mammalian cells His
Mouse Mpo-2637M Recombinant Mouse Mpo protein, His-tagged E.coli His Val139~Gly252 (Accession # P11247)
Mouse Mpo-2638M Recombinant Mouse Mpo protein, His-tagged E.coli His Leu253~Thr718 (Accession # P11247)
Mouse MPO-9990M Recombinant Mouse MPO Protein Mammalian Cell His
Mouse Mpo-52M Recombinant Mouse Mpo Protein, His-tagged Human Cells His
Mouse Mpo-4123M Recombinant Mouse Mpo Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Mpo-5650M Recombinant Mouse Mpo Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Mpo-5650M-B Recombinant Mouse Mpo Protein Pre-coupled Magnetic Beads HEK293
Rat Mpo-2639R Recombinant Rat Mpo protein, His & T7-tagged E.coli His/T7 Val134~Gly263 (Accession # D3ZGE2)
Rat Mpo-1790R Recombinant Rat Mpo Protein, His-tagged E.coli N-His Val252-Thr458
Cattle MPO-1133C Recombinant Cattle MPO Protein, His&GST-tagged E.coli N-His&GST Val139-Gly252
Kit-2293 Myeloperoxidase (MPO) Fluorometric Activity Assay Kit N/A
Kit-2292 Myeloperoxidase (MPO) Colorimetric Activity Assay Kit N/A
Kit-0604 MPO Inhibitor Screening Assay Kit N/A
Kit-0603 Fluorescent Myeloperoxidase and Chlorination Detection Kit N/A
Kit-0605 Myeloperoxidase Fluorometric Detection Kit N/A
Kit-1982 Myeloperoxidase Inhibitor Screening Assay Kit N/A
Kit-0606 Myeloperoxidase Chlorination Fluorometric Assay Kit N/A
Kit-0607 Myeloperoxidase Peroxidation Fluorometric Assay Kit N/A
Kit-1986 Neutrophil Myeloperoxidase Activity Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MPO Related Research Area

MPO involved in several pathways and played different roles in them. We selected most pathways MPO participated on our site, such as Phagosome, Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with MPO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
PhagosomeATP6V0E1;TUBB5;TUBB2B;TUBB;C3A.2;ABCB3L1;TUBA2;TUBA8L;VAMP3
Transcriptional misregulation in cancerMPO;MMP3;ARNT2;BCL2L1;HOXA11;MLLT1;CCNT1;CCNT2;BMP2K

MPO has several biochemical functions, for example, chromatin binding, heme binding, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MPO itself. We selected most functions MPO had, and list some proteins which have the same functions with MPO. You can find most of the proteins on our site.

Function Related Protein
chromatin bindingRNF20;MEIS3;NCOA5;CNBPA;GABPA;YBX1;SKI;SIX1;KDM8
heme bindingDUOX2;CYP7A1A;CYP2K22;CYP7A1;CYP2P6;CYP2A13;HBAA1;HBG2;CYGB
heparin bindingABP1;BMP7;PCOLCE2;APLP1;VEGFAA;PTCH1;SELL;ADAMTSL5;RPL22
metal ion bindingBSN;PGGT1B;UQCRC2B;HDHD2;ZFP110;BCMO1;OSGEPL1;SP9;AKAP13
peroxidase activityGPX8;GPX4B;PTGS2A;EPX;GPX7;DUOX2;IPCEF1;CYGB;MGST3

MPO has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MPO here. Most of them are supplied by our site. Hope this information will be useful for your research of MPO.

Dynll1; ssrna_ug

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