| Description : |
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
45.7 kDa |
| AA Sequence : |
MAERRRHKKRIQEVGEPSKEEKAVA KYLRFNCPTKSTNMMGHRVDYFIAS KAVDCLLDSKWAKAKKGEEALFTTR ESVVDYCNRLLKKQFFHRALKVMKM KYDKDIKKEKDKGKAESGKEEDKKS KKENIKDEKTKKEKEKKKDGEKEES KKEETPGTPKKKETKKKFKLEPHDD QVFLDGNEVYVWIYDPVHFKTFVMG LILVIAVIAATLFPLWPAEMRVGVY YLSVGAGCFVASILLLAVARCILFL IIWLITGGRHHFWFLPNLTADVGFI DSFRPLYTHEYKGPKADLKKDEKSE TKKQQKSDSEEKSDSEKKEDEEGKV GPGNHGTEGSGGERHSDTDSDRRED DRSQHSSGNGNDFEMITKEELEQQT DGDCEEDEEEENDGETPKSSHEKST RTRPLEQKLISEEDLAANDILDYKD DDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
