Recombinant Mouse Sec62 Protein, Myc/DDK-tagged

• Cat.No.: Sec62-5752M
• Product Overview: Purified recombinant protein of mouse full-length SEC62 homolog (S. cerevisiae) (Sec62), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Mediates post-translational transport of precursor polypeptides across endoplasmic reticulum (ER). Proposed to act as a targeting receptor for small presecretory proteins containing short and apolar signal peptides. Targets and properly positions newly synthesized presecretory proteins into the SEC61 channel-forming translocon complex, triggering channel opening for polypeptide translocation to the ER lumen.
• Molecular Mass: 45.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Sec62 SEC62 homolog (S. cerevisiae) [ Mus musculus (house mouse) ]
• Official Symbol: Sec62
• Synonyms: Sec62; SEC62 homolog (S. cerevisiae); Dtr; HTP; Tlo; HTP1; SEC6; Dtrp1; Tloc1; AI844545; AW545092; 3100002M17Rik; translocation protein SEC62; TP-1; translocation protein 1
• Gene ID: 69276
• mRNA Refseq: NM_027016
• Protein Refseq: NP_081292
• UniProt ID: Q8BU14