| Description : |
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
60 kDa |
| Protein Length : |
610 |
| AA Sequence : |
MIASQFLSALTLVLLIKESGAWSYN TSTEAMTYDEASAYCQQRYTHLVAI QNKEEIEYLNSILSYSPSYYWIGIR KVNNVWVWVGTQKPLTEEAKNWAPG EPNNRQKDEDCVEIYIKREKDVGMW NDERCSKKKLALCYTAACTNTSCSG HGECVETINNYTCKCDPGFSGLKCE QIVNCTALESPEHGSLVCSHPLGNF SYNSSCSISCDRGYLPSSMETMQCM SSGEWSAPIPACNVVECDAVTNPAN GFVECFQNPGSFPWNTTCTFDCEEG FELMGAQSLQCTSSGNWDNEKPTCK AVTCRAVRQPQNGSVRCSHSPAGEF TFKSSCNFTCEEGFMLQGPAQVECT TQGQWTQQIPVCEAFQCTALSNPER GYMNCLPSASGSFRYGSSCEFSCEQ GFVLKGSKRLQCGPTGEWDNEKPTC EAVRCDAVHQPPKGLVRCAHSPIGE FTYKSSCAFSCEEGFELHGSTQLEC TSQGQWTEEVPSCQVVKCSSLAVPG KINMSCSGEPVFGTVCKFACPEGWT LNGSAARTCGATGHWSGLLPTCEAP TESNIPLVAGLSAAGLSLLTLAPFL LWLRKCLRKAKKFVPASSCQSLESD GSYQKPSYIL |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
