Active Recombinant Rat Sele protein(Met1-Pro494), His-tagged

• Cat.No.: Sele-4093R
• Product Overview: Recombinant Rat Sele protein(P98105-1)(Met1-Pro494), fused with C-terminal His tag, was expressed in HEK293.

Specification

• similar: Sele
• Alias: SELE; selectin E; E-selectin; ELAM-1; LECAM2; selectin, endothelial cell; CD62 antigen-like family member E; endothelial leukocyte adhesion molecule 1; leukocyte-endothelial cell adhesion molecule 2
• Source: HEK293
• Species: Rat
• Conjugate: C-His
• Tag: His
• Protein length: Met1-Pro494
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• MolecularMass: The recombinant rat SELE comprises 484 amino acids and predicts a molecular mass of 53 kDa. The apparent molecular mass of the rat SELE is approximately 70-80 kDa in SDS-PAGE under reducing conditions due to glycosylation.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 97 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
• GeneName: Sele selectin E [ Rattus norvegicus ]
• GeneNameWeblink: 25544
• OfficialSymbol: Sele
• OfficialSymbolWeblink: 25544
• GeneIDWeblink: 25544
• mRNARefseq: NM_138879
• mRNARefseqWeblink: NM_138879.1
• ProteinRefseqWeblink: NP_620234.1
• Synonyms: SELE; selectin E; E-selectin; ELAM-1; LECAM2; selectin, endothelial cell; CD62 antigen-like family member E; endothelial leukocyte adhesion molecule 1; leukocyte-endothelial cell adhesion molecule 2
• Gene ID: 25544

Gene Information

• Synonyms: SELE; selectin E; E-selectin; ELAM-1; LECAM2; selectin, endothelial cell; CD62 antigen-like family member E; endothelial leukocyte adhesion molecule 1; leukocyte-endothelial cell adhesion molecule 2
• Gene ID: 25544

Reviews

11/26/2020

With its remarkable purity and reliability, coupled with the manufacturer's excellent technical support, this protein is a crucial asset in addressing my scientific inquiries and advancing my research goals.

09/08/2019

In addition to its outstanding quality, the SELE Protein exhibits exceptional stability during storage and usage.

06/16/2019

Its ability to maintain structural integrity and stability ensures accurate imaging, enabling me to gain deeper insights into the three-dimensional organization and interactions of the proteins under investigation.

Q&As

Is there a diagnostic test to measure SELE levels in patients?

Some diagnostic tests can measure SELE levels in the blood, providing insights into the inflammatory status of an individual.

Can SELE protein be involved in cancer progression?

Emerging research suggests a potential role of SELE in cancer metastasis, making it a target for investigation in cancer therapy.

Are there any genetic factors influencing SELE expression?

Genetic variations can influence SELE expression, contributing to individual differences in inflammatory responses.

How does SELE protein interact with circulating immune cells?

SELE binds to specific receptors on immune cells, facilitating their adhesion to endothelial cells and promoting their migration to inflammatory sites.

Can targeting SELE protein be a potential strategy for anti-inflammatory therapies?

Yes, drugs designed to modulate SELE activity are being explored as potential anti-inflammatory agents.