Recombinant Human TREM2 Protein, GST/His-tagged

• Cat.No.: TREM2-02H
• Product Overview: Purified recombinant protein of Human triggering receptor expressed on myeloid cells 2 (TREM2), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli.

Specification

• Description: This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: E. coli
• Species: Human
• Tag: GST/His
• Molecular Mass: 51.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris, pH8.0, 150 mM NaCl, 10% glycerol,1% Sarkosyl.

Gene Information

• Gene Name: TREM2 triggering receptor expressed on myeloid cells 2 [ Homo sapiens (human) ]
• Official Symbol: TREM2
• Synonyms: TREM2; triggering receptor expressed on myeloid cells 2; PLOSL2; TREM-2; Trem2a; Trem2b; Trem2c; triggering receptor expressed on myeloid cells 2; triggering receptor expressed on monocytes 2; triggering receptor expressed on myeloid cells 2a
• Gene ID: 54209
• mRNA Refseq: NM_018965
• Protein Refseq: NP_061838
• MIM: 605086
• UniProt ID: Q9NZC2