Recombinant Human TTR Protein, MYC/DDK-tagged

• Cat.No.: TTR-2922H
• Product Overview: Recombinant Human TTR protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 13.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: TTR transthyretin [ Homo sapiens ]
• Official Symbol: TTR
• Synonyms: CTS; CTS1; HEL111; HsT2651; PALB; TBPA
• Gene ID: 7276
• mRNA Refseq: NM_000371
• Protein Refseq: NP_000362
• MIM: 176300
• UniProt ID: P02766