Recombinant Mouse Crtc1 Protein, Myc/DDK-tagged
Cat.No. : | Crtc1-2322M |
Product Overview : | Purified recombinant protein of mouse full-length CREB regulated transcription coactivator 1 (Crtc1), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated. Acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons. In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 66.9 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Crtc1 CREB regulated transcription coactivator 1 [ Mus musculus (house mouse) ] |
Official Symbol : | Crtc1 |
Synonyms : | Crtc1; CREB regulated transcription coactivator 1 |
Gene ID : | 382056 |
mRNA Refseq : | NM_001004062 |
Protein Refseq : | NP_001004062 |
UniProt ID : | Q68ED7 |
Products Types
◆ Recombinant Protein | ||
CRTC1-1991M | Recombinant Mouse CRTC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CRTC1-3344H | Recombinant Human CRTC1 Protein, MYC/DDK-tagged | +Inquiry |
CRTC1-1916H | Recombinant Human CRTC1 Protein, GST-tagged | +Inquiry |
CRTC1-1265R | Recombinant Rat CRTC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CRTC1-666H | Recombinant Human CRTC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CRTC1-202HCL | Recombinant Human CRTC1 lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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