Recombinant Mouse Serine (or cysteine) Peptidase Inhibitor, Clade I, Member 1

• Cat.No.: Serpini1-5518M
• Product Overview: Recombinant Mouse Serpini1is produced as a fusion protein with a proprietary purification tag. The tagis removed by TEV cleavage after purification.

Specification

• Cat. No.: Serpini1-5518M
• Description: Serpini1 isassociated with Familial encephalopathy with neuroserpin inclusion bodies.Serine protease inhibitors of the serpin superfamily are involved in manycellular processes. Serpini1 was first identified as a protein secreted fromthe axons of dorsal root ganglion neurons. It is expressed in the late stagesof neurogenesis during the process of synapse formation.
• Source: Insect cells
• Species: Mouse
• Form: Frozen liquid in0.05M Sodium Phosphate Buffer + 0.3M NaCl, pH 7.4.
• Molecular Weight: 49 kDa
• Concentration: 1.0 mg/ml
• Purity: >95% by SDS-PAGEanalysis
• Endotoxin Level: < 0.1 ng/µg ofprotein
• Storage: Store at -80°C.Stable for 3 years from delivery. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: Serpini1

Gene Information

• Gene Name: Serpini1 serine (or cysteine)peptidase inhibitor, clade I, member 1 [ Mus musculus ]
• Synonyms: Serpini1; serine (orcysteine) peptidase inhibitor, clade I, member 1; Ns; PI12; PI-12; Spi17;AI837402; neuroserpin; serpin I1; OTTMUSP00000024524; protease inhibitor 17;peptidase inhibitor 12; serine protease inhibitor 17
• Gene ID: 20713
• mRNA Refseq: NM_009250
• Protein Refseq: NP_033276
• UniProt ID: O35684
• Chromosome Location: 3 E3; 3
• Function: peptidase inhibitoractivity; serine-type endopeptidase inhibitor activity

Reviews

12/12/2022

It has strong specificity and selectivity for the target of action, which is suitable for experiments.

01/09/2022

The effect is good and has a significant effect on cell growth and proliferation.

12/30/2020

Good crystallinity, suitable for crystallography research.

Q&As

What role does SERPINI1 protein play in the prognosis of neurological disorders?

SERPINI1 proteins may play different roles in the prognosis of different neurological diseases, and further research will help us better understand their specific role in prognosis

Can SERPINI1 protein be a potential therapeutic target?

Because of its role in neurological disorders, SERPINI1 protein is thought to be a potential target for the treatment of these diseases. However, more research is needed to verify its feasibility.

What is the role of SERPINI1 protein in neurological disorders?

In some cases, mutations in SERPINI1 proteins can lead to problems with nerve cell connectivity, affecting the normal function of the nervous system, leading to neurological disorders.

Is SERPINI1 protein related to drug therapy?

Research on SERPINI1 protein is still in its infancy, so there is no specific drug needle to treat it.

Which is the main physiological functions of SERPINI1 protein?

SERPINI1 proteins are mainly involved in synaptic breeding and the formation of neuronal connections in nerve cells, and play an important role in the normal function of the nervous system.

How to detect the expression of SERPINI1 proteins?

Commonly used methods include immunohistochemistry, western blotting, and immunohistochemical staining.