| Description : |
Enables several functions, including androgen binding activity; androgen receptor binding activity; and nuclear receptor activity. Involved in several processes, including cellular response to hormone stimulus; mating; and regulation of transcription, DNA-templated. Located in several cellular components, including axon; dendrite; and nucleus. Used to study hypertension; osteoporosis; prostate adenocarcinoma; prostate cancer; and prostatic hypertrophy. Biomarker of acute kidney failure and androgen insensitivity syndrome. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; conduct disorder; disorder of sexual development (multiple); reproductive organ cancer (multiple); and spinal muscular atrophy (multiple). Orthologous to human AR (androgen receptor). |
| Source : |
E. coli |
| Species : |
Rat |
| Tag : |
N-His |
| Protein length : |
Full Length |
| Molecular Mass : |
99 kDa |
| AA Sequence : |
MHHHHHHHHLRMEVQLGLGRVYPRP PSKTYRGAFQNLFQSVREAIQNPGP RHPEAASIAPPGACLQQRQETSPRR RRRQQHPEDGSPQAHIRGTTGYLAL EEEQQPSQQQSASEGHPESGCLPEP GAATAPGKGLPQQPPAPPDQDDSAA PSTLSLLGPTFPGLSSCSADIKDIL SEAGTMQLLQQQQQQQQQQQQQQQQ QQQQQQEVISEGSSSVRAREATGAP SSSKDSYLGGNSTISDSAKELCKAV SVSMGLGVEALEHLSPGEQLRGDCM YASLLGGPPAVRPTPCAPLAECKGL SLDEGPGKGTEETAEYSSFKGGYAK GLEGESLGCSGSSEAGSSGTLEIPS SLSLYKSGAVDEAAAYQNRDYYNFP LALSGPPHPPPPTHPHARIKLENPS DYGSAWAAAAAQCRYGDLASLHGGS VAGPSTGSPPATASSSWHTLFTAEE GQLYGPGGGGGSSSPSDAGPVAPYG YTRPPQGLASQEGDFSASEVWYPGG VVNRVPYPSPSCVKSEMGPWMENYS GPYGDMRLDSTRDHVLPIDYYFPPQ KTCLICGDEASGCHYGALTCGSCKV FFKRAAEGKQKYLCASRNDCTIDKF RRKNCPSCRLRKCYEAGMTLGARKL KKLGNLKLQEEGENSSAGSPTEDPS QKMTVSHIEGYECQPIFLNVLEAIE PGVVCAGHDNNQPDSFAALLSSLNE LGERQLVHVVKWAKALPGFRNLHVD DQMAVIQYSWMGLMVFAMGWRSFTN VNSRMLYFAPDLVFNEYRMHKSRMY SQCVRMRHLSQEFGWLQITPQEFLC MKALLLFSIIPVDGLKNQKFFDELR MNYIKELDRIIACKRKNPTSCSRRF YQLTKLLDSVQPIARELHQFTFDLL IKSHMVSVDFPEMMAEIISVQVPKI LSGKVKPIYFHTQ |
| Purity : |
> 90% by SDS-PAGE |
| Storage : |
Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Concentration : |
0.59 mg/mL by BCA |
| Storage Buffer : |
Sterile PBS, pH7.4, 1mM DTT |
