Recombinant Active Rat Ar Protein (Ligand Binding Domain), GST/His-tagged

• Cat.No.: Ar-01R
• Product Overview: Recombinant androgen receptor ligand binding domain (AR-LBD) is a rat protein, expressed as a GST- and His-tagged protein in insect cells. AR-LBD is expressed and purified in the absence of exogenous ligands, making it ideal for ligand-binding and coregulator recruitment studies.

Specification

• Description: Enables several functions, including androgen binding activity; androgen receptor binding activity; and nuclear receptor activity. Involved in several processes, including cellular response to hormone stimulus; mating; and regulation of transcription, DNA-templated. Located in several cellular components, including axon; dendrite; and nucleus. Used to study hypertension; osteoporosis; prostate adenocarcinoma; prostate cancer; and prostatic hypertrophy. Biomarker of acute kidney failure and androgen insensitivity syndrome. Human ortholog(s) of this gene implicated in several diseases, including attention deficit hyperactivity disorder; conduct disorder; disorder of sexual development (multiple); reproductive organ cancer (multiple); and spinal muscular atrophy (multiple). Orthologous to human AR (androgen receptor).
• Source: Insect cells
• Species: Rat
• Tag: GST/His
• Molecular Mass: 64.42 kDa
• Storage: Store in ultra-cold freezer (-68 to -85 centigrade).

Gene Information

• Gene Name: Ar androgen receptor [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Ar
• Synonyms: Ar; androgen receptor; Tfm; Andr; androgen receptor; androgen receptor (Testicular feminization), same as Tfm; dihydrotestosterone receptor; nuclear receptor subfamily 3 group C member 4
• Gene ID: 24208
• mRNA Refseq: NM_012502
• Protein Refseq: NP_036634
• UniProt ID: A0A0G2JSI8