Native Human Apolipoprotein C-I


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Native Human Apolipoprotein C-I

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Cat. No. : APOC1-616H
Product Overview : Native human APOC1was expressed in human plasma. Its molecular weight is 6600 Dalton.
Description : HumanApolipoprotein CI (APOC1) is a lipoprotein with a length of 57 amino acids.Human APOC1 is one of the most positively charged proteins in the humanbody. The main function of APOC1 is inhibition of CETP, probably byaltering the electric charge of HDL molecules. Recent studies have suggestedthat APOC1 in very low-density lipoprotein (VLDL) plays an important role incausing hypertriglyceridemia independent of APOC3, which is associated withcoronary heart disease (CHD). APOC1 has been found to activate LCAT. Thenormal plasma concentration of APOC1 is 4-7 mg/dl.
Form : Liquidin 75 mM PBS pH 7.4 + 75 mM NaCl + 75 mM EDTA.
Source : Human plasm
Concentration : 6.6 kDa
MolecularWeight : > 99% by SDS-PAGE
Purity : Store at -20°C.Avoid repeated freeze-thaw cycles.
Storage : Liquidin 75 mM PBS pH 7.4 + 75 mM NaCl + 75 mM EDTA.
OfficialSymbol : APOC1
PDB rendering basedon 1ioj. :

Gene Name : APOC1 apolipoprotein C-I [ Homosapiens ]
Synonyms : APOC1;apolipoprotein C-I; ALPCI; Apoc1; LRRG0; apo-CIB; apoC-IB; apolipoprotein C1;ApoC-IB; Apo-CIB; APOC1B; Apolipoprotein C-I; Apolipoprotein C1; Apo-CIB";ApoC-IB"
Gene ID : 341
mRNA Refseq : NM_001645
Protein Refseq : NP_001636
MIM : 107710
UniProt ID : P02654
Chromosome Location : 19q13.2
Pathway : Statin Pathway
Function : fatty acid binding;lipase inhibitor activity; phosphatidylcholine binding;phosphatidylcholine-sterol O-acyltransferase activator activity;phospholipase inhibitor activity

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