Native Human ApoC-I

• Cat.No.: ApoC-I-3557H

Specification

• Description: The protein encoded by this gene is a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
• Source: Human plasma
• Species: Human
• Form: Lyophilized from 10mM NH4HCO3, pH 7.4.
• Molecular Mass: 6.6 kDa
• Purity: >95% pure by SDS PAGE
• Notes: Small volumes of ApoC-I native protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles.
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: APOC1 apolipoprotein C-I [ Homo sapiens ]
• Official Symbol: APOC1
• Synonyms: APOC1; apolipoprotein C-I; apo-CIB; apoC-IB; apolipoprotein C1
• Gene ID: 341
• mRNA Refseq: NM_001645
• Protein Refseq: NP_001636
• MIM: 107710
• UniProt ID: P02654
• Chromosome Location: 19q13.2
• Pathway: Statin Pathway, organism-specific biosystem
• Function: fatty acid binding; lipase inhibitor activity; phosphatidylcholine binding; phosphatidylcholine-sterol O-acyltransferase activator activity; phospholipase inhibitor activity