Recombinant Human Laminin α4, GST-Tagged

• Cat.No.: LAMA4-6956H
• Product Overview: The protein wasexpressed as gst-tagged fusion protein by E.Coli and puried by GSH-sepharose. The puried protein was resolved in 1M P BS (58mM Na2HP O4,17mMNaH2P O4, 68mM NaCl, pH8. ) added with 100mM GS H and 1% TritonX-100,15%glycerol

Specification

• Cat. No.: LAMA4-6956H
• Description: Laminin subunitalpha-4 is a protein that in humans is encoded by the LAMA4 gene. Laminins, afamily of extracellular matrix glycoproteins, are the major noncollagenousconstituent of basement membranes. They have been implicated in a widevariety of biological processes including cell adhesion, differentiation,migration, signaling, neurite outgrowth and metastasis. Laminins are composedof 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, andB2, respectively) and they form a cruciform structure consisting of 3 shortarms, each formed by a different chain, and a long arm composed of all 3chains. Each laminin chain is a multidomain protein encoded by a distinctgene. Several isoforms of each chain have been described
• Host: E.Coli
• Purity: puried by GSH-sepharose
• Format: 1M P BS (58mM Na2HPO4,17mM NaH2P O4, 68mM NaCl,pH8. ) added with100mM GS H and 1% Triton X-100,15%glycerol
• Storage: Theprotein is stored in P BS buer at -20 oC.Repeated freeze- thaw cycles should be avoided.

Gene Information

• Gene Name: LAMA4 laminin, alpha 4 [ Homosapiens ]
• Official Symbol: LAMA4
• Synonyms: LAMA4;laminin, alpha 4; LAMA3; LAMA4*-1; DKFZp686D23145; Laminin-14 subunit alpha;Laminin-8 subunit alpha; Laminin-9 subunit alpha
• Gene ID: 3910
• mRNA Refseq: NM_001105206
• Protein Refseq: NP_001098676
• MIM: 600133
• UniProt ID: Q16363
• Chromosome Location: 6q21
• Pathway: extracellularmatrix structural constituent; receptor binding
• Function: Africantrypanosomiasis; Amoebiasis; ECM-receptor interaction; FOXM1 transcriptionfactor networ; Focal adhesion; Pathways in cancer; Small cell lung cancer;Toxoplasmosis