"SEPT6" Related Products

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Recombinant Human Septin 6, His-tagged

Cat.No.: SEPT6-6885H
Product Overview: Recombinant human SEPT6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 52.1 kDa.
Description: Septins belong to the GTPase superclass of proteins and have been functionally implicated in cytokinesis and the maintenance of cellular morphology. SEPT6 is member of septin family and interact with SEPT2. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 100mM NaCl.
Molecular Mass: 52.1kDa (457aa)
Protein length: 1-434aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAATDIA RQVGEGCRTV PLAGHVGFDS LPDQLVNKSV SQGFCFNILC VGETGLGKST LMDTLFNTKF EGEPATHTQP GVQLQSNTYD LQESNVRLKL TIVSTVGFGD QINKEDSYKP IVEFIDAQFE AYLQEELKIR RVLHTYHDSR IHVCLYFIAP TGHSLKSLDL VTMKKLDSKV NIIPIIAKAD AISKSELTKF KIKITSELVS NGVQIYQFPT DDESVAEING TMNAHLPFAV IGSTEELKIG NKMMRARQYP WGTVQVENEA HCDFVKLREM LIRVNMEDLR EQTHTRHYEL YRRCKLEEMG FKDTDPDSKP FSLQETYEAK RNEFLGELQK KEEEMRQMFV QRVKEKEAEL KEAEKELHEK FDRLKKLHQD EKKKLEDKKK SLDDEVNAFK QRKTAAELPQ SQGSQAGGSQ TLKRDKEKKN NPWLCTE
Purity: >90% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration: 0.5mg/ml (determined by Bradford assay)
Gene Name: SEPT6 septin 6 [ Homo sapiens ]
Official Symbol: SEPT6
Synonyms: SEPT; septin 6; SEP2; SEPT2; RP5-876A24.2; septin-6; septin 2; KIAA0128; MGC16619; MGC20339; Nkrf; RCG53214, isoform CRA_d; SEPT6/MLL FUSION GENE; SEPT6_HUMAN
Gene ID: 23157
mRNA Refseq: NM_145802
Protein Refseq: NP_665801
MIM: 300683
UniProt ID: Q14141
Chromosome Location: Xq24
Function: GTP binding; protein binding

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